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- Clone
- LK26 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Folate receptor alpha, FR-alpha, KB cells FBP, folate binding protein, folate receptor, adult, adult folate-binding protein, ovarian tumor-associated antigen MOv18
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
KB cells were stained with anti-FOLR1 (clone LK26) PE (closed histogram) or with mouse IgG2a, κ PE isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 908303 | 25 tests | $153 | ||||
| 908304 | 100 tests | $360 | ||||
Folate receptor (FOLR1), also known as folate receptor alpha, is a folate-binding protein (FBP) expressed in adults. It has high affinity for folic acid and its metabolites, including 5-methyltetrahydrofolate (5-MTF), the biologically active form of folic acid used for DNA synthesis and the cysteine cycle. FOLR1 mediates intracellular delivery of 5-MTF. FOLR1 is overexpressed in a variety of tumors, including breast, colorectal, and brain.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against gestational choriocarcinoma cell line, Lu-75 and detects folate-binding protein (FBP).
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
This antibody is effective in immunohistochemistry (IHC) and immunoprecipitation (IP).
Positive tissue (human): Frozen placenta or ovarian carcinoma
The LK26 antigen is a 35-40 kD cell surface glycoprotein expressed in normal placenta and gestational choriocarcinoma. -
Application References
(PubMed link indicates BioLegend citation) -
- Hviid TV, et al. 1999. Prenat Diagn. 19: 271.
- Chesa-Garin P, et al. 1993. Am J Pathol. 142: 557.
- Rettig WJ, et al. 1985. Int J Cancer. 35:469.
- Product Citations
-
- RRID
-
AB_2629794 (BioLegend Cat. No. 908303)
AB_2629794 (BioLegend Cat. No. 908304)
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All FOLR1 (Folate Binding Protein) Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-FOLR1 (Folate Binding Protein) | LK26 | IHC-F |
| PE anti-FOLR1 (Folate Binding Protein) | LK26 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-FOLR1 (Folate Binding Protein)
IHC staining of purified anti-FOLR1 (Folate Binding Protein)... -
PE anti-FOLR1 (Folate Binding Protein)
KB cells were stained with anti-FOLR1 (clone LK26) PE (close...
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