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PE anti-human CD138 (Syndecan-1) Antibody

Pricing & Availability
Clone
S22003D (See other available formats)
Regulatory Status
RUO
Other Names
Syndecan-1, B-B4
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
S22003D_PE_CD138_Antibody_030824
Human myeloma cell line U266 was stained with anti-human CD138 (Syndecan-1) (clone S22003D) PE (filled histogram) or rat IgG2b, κ PE isotype control (open histogram).
  • S22003D_PE_CD138_Antibody_030824
    Human myeloma cell line U266 was stained with anti-human CD138 (Syndecan-1) (clone S22003D) PE (filled histogram) or rat IgG2b, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Quantity Check Availability Save
390105 25 tests $105
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390106 100 tests $270
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Description

CD138, also known as Syndecan-1, is a type I integral membrane heparin sulfate proteoglycan.  As a member of the syndecan protein family, Syndecan-1 mediates multiple cellular processes, including migration, proliferation, and cell-matrix adhesion through interactions with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant human syndecan-1 protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone S22003D can block the binding of clone MI15 on target cells, but it does not affect the binding of clones DL-101, S22003B, and S22003F on target cells.

Binding of clone S22003D on fixed target cells is not significantly reduced compared to un-fixed cells.

RRID
AB_3106068 (BioLegend Cat. No. 390105)
AB_3106068 (BioLegend Cat. No. 390106)

Antigen Details

Structure
100-200 kD type I integral transmembrane glycoprotein
Distribution

Plasma cells, pre-B cells, epithelial cells, endothelial cells

Function
Adhesion, controls cell morphology, regulates cell growth
Ligand/Receptor
FGFb, collagen, fibronectin
Cell Type
B cells, Endothelial cells, Epithelial cells, Plasma cells
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Sanderson RD, et al. 1992. Cell Regul. 1:27.
  2. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers. Wiley-Liss A John Wiley & Sons Inc, Publication.
Gene ID
6382 View all products for this Gene ID
UniProt
View information about CD138 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 03/08/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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