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PE anti-human CD26 Antibody

Pricing & Availability
Clone
5-109 (See other available formats)
Regulatory Status
RUO
Other Names
ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
5-109_PE_CD26_Antibody_071624
Human peripheral blood lymphocytes were stained with anti-human CD3 (clone UCHT1) APC and anti-human CD26 (clone 5-109) PE (left) or mouse IgG1, κ PE isotype control (right).
  • 5-109_PE_CD26_Antibody_071624
    Human peripheral blood lymphocytes were stained with anti-human CD3 (clone UCHT1) APC and anti-human CD26 (clone 5-109) PE (left) or mouse IgG1, κ PE isotype control (right).
See PE spectral data
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335307 25 tests $105
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335308 100 tests $235
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Description

CD26, also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV), is a 110 kD type II membrane protein. It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45, and ADA.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Test clone 5-109 and reference clone BA5b completely cross-block the staining on target cells.

RRID
AB_3662229 (BioLegend Cat. No. 335307)
AB_3662229 (BioLegend Cat. No. 335308)

Antigen Details

Structure
Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
Distribution

Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages

Function
Dipeptidyl peptidase, T cell costimulation, HIV entry
Ligand/Receptor
Adenosine-deaminase, collagen
Cell Type
B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Kameoka J, et al. 1993. Science. 261:466-9.
  2. Dang NH, et al. 1990. J Exp Med. 172:649-52.
Gene ID
1803 View all products for this Gene ID
UniProt
View information about CD26 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 07/16/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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