Loading...

PE anti-human EPHB6 Antibody

Pricing & Availability
Clone
T49-25 (See other available formats)
Regulatory Status
RUO
Other Names
Ephrin Type-B Receptor 6, Eph receptor B6, tyrosine-protein kinase-defective receptor B6
Isotype
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
publications
T49-25_PE_-EPHB6_FC_052523
Human peripheral blood lymphocytes were stained with anti-human EPHB6 (clone T49-25) PE (left) or mouse IgG1, κ PE isotype control (right). Cells were costained with anti-human CD3 APC.
  • T49-25_PE_-EPHB6_FC_052523
    Human peripheral blood lymphocytes were stained with anti-human EPHB6 (clone T49-25) PE (left) or mouse IgG1, κ PE isotype control (right). Cells were costained with anti-human CD3 APC.
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
384303 25 tests $194
Check Availability


Need larger quantities of this item?
Request Bulk Quote
384304 100 tests $382
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

EPHB6 is a 110 kD protein transmembrane protein of the ephrin receptor family of tyrosine kinases, but lacks kinase activity. It is expressed on skin keratinocytes, neurons, thymocytes, immature T Cells, and a small population of peripheral CD4+ T Cells and CD8+ T Cells. Loss of EPHB6 expression has been related with increased metastatic melanoma and neuroblastoma, suggesting a role in suppressing tumorigenicity.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
GST-fusion extracellular domain region 3 of human EPHB6 recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_3068062 (BioLegend Cat. No. 384303)
AB_3068062 (BioLegend Cat. No. 384304)

Antigen Details

Structure
110 kD transmembrane protein, tyrosine kinase
Distribution

T lymphocytes, thymocytes, neurons, keratinocytes

Ligand/Receptor
Ephrin B6, Ephrin B2, Ephrin B1
Cell Type
Neurons, T cells
Biology Area
Cancer Biomarkers, Cell Biology, Immunology, Neuroscience
Antigen References
  1. Matsuoka H, et al. 2005. J Biol Chem. 280:29355-63
  2. Strozen T, et al. 2021. Int J Mol Sci. 22:821
  3. Zhou R. 1998. Pharm Ther. 77:151-81
Gene ID
2051 View all products for this Gene ID
UniProt
View information about EPHB6 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 05/25/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account