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PE anti-human PSMA (FOLH1) Antibody

Pricing & Availability
Clone
LNI-17 (See other available formats)
Regulatory Status
RUO
Other Names
PSM, Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), NAALADase I, FGCP
Isotype
Mouse IgG1, κ
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Product Citations
publications
LNI-17_PE_050609.jpg
Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 PE
  • LNI-17_PE_050609.jpg
    Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 PE
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342503 25 tests $171
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342504 100 tests $360
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Description

PSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), and NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). PSMA is expressed by normal and malignant prostate epithelial cells, by urothelial adenocarcinoma, and vasculatures of other malignancies. It is also found in the nervous system.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Sayar E, et al. 2023. JCI Insight. 8:. PubMed
  2. Mentink A, et al. 2023. Sci Rep. 13:6051. PubMed
  3. Reichenbach P, et al. 2023. Nat Biomed Eng. . PubMed
RRID
AB_2247193 (BioLegend Cat. No. 342503)
AB_2247193 (BioLegend Cat. No. 342504)

Antigen Details

Structure
Type II transmembrane zinc metallopeptidase, M28 peptidase family
Distribution

Epithelial cells in prostate, intestine and kidney tissue, nervous system

Function
Hydrolyzing enzyme activity
Cell Type
Epithelial cells
Biology Area
Cell Biology
Antigen References

1. Silver DA, et al. 1997. Clin. Cancer Res. 3:81.
2. Troyer JK, et al. 1995. Int. J. Cancer. 62:552.
3. Mannweiler S, et al. 2009. Pathol. Oncol. Res. 15:167.

Gene ID
2346 View all products for this Gene ID
UniProt
View information about PSMA on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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