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PE anti-mouse CD52 Antibody

Pricing & Availability
Clone
S20005A (See other available formats)
Regulatory Status
RUO
Other Names
CAMPATH-1 antigen
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
S20005A_PE_CD52_Antibody_030124
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 (clone 17A2) APC and anti-mouse CD52 (clone S20005A) PE (left) or rat Ig2a, κ PE isotype control (right).
  • S20005A_PE_CD52_Antibody_030124
    C57BL/6 mouse splenocytes were stained with anti-mouse CD3 (clone 17A2) APC and anti-mouse CD52 (clone S20005A) PE (left) or rat Ig2a, κ PE isotype control (right).
See PE spectral data
Cat # Size Price Quantity Check Availability Save
165705 25 µg $177
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165706 100 µg $384
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Description

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene. It is expressed in the embryo mesenchyme and thymus primordium. CD52 acts upstream of or within response to bacterium and is located in the sperm midpiece. CD52 is present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It also is found on monocytes and dendritic cells. Furthermore, it is found within the male genital tract and is present on the surface of mature sperm cells. Due to its highly negative charge and presence on sperm cells and lymphocytes, it has been thought that CD52 functions as an anti-adhesion since it allows cells to freely move around.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_3662205 (BioLegend Cat. No. 165705)
AB_3662205 (BioLegend Cat. No. 165706)

Antigen Details

Structure
CD52 is a peptide of 12 amino acids, anchored to glycosylphosphatidylinositol (GPI).
Distribution

Expressed on lymphohematopoietic tissues, including thymus, spleen, and bone marrow, but not in liver, kidney, and brain.

Function
Promote cell-mediated killing (antibody-dependent cellular cytotoxicity)
Cell Type
B cells, Eosinophils, Erythrocytes, Macrophages, Monocytes, T cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Gudrun R, et al. 2002. Blood. 101:1422.
Gene ID
23833 View all products for this Gene ID
UniProt
View information about CD52 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 03/01/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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