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PE/Cyanine7 anti-human TCR Vβ13.1 Antibody

Pricing & Availability
Clone
H131 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor Vβ13.1 chain, TCRBV13.1, TCRBV13
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
H131_PECyanine7_TCR-VB131_Antibody_1_111623
Human peripheral blood lymphocytes were stained with CD3 APC and with the anti-TCR Vß13.1 (clone H131) PE/Cyanine7 (left) or PE/Cyanine7 mouse IgG2b, κ isotype control (right). Data shown was gated on the lymphocyte population.
  • H131_PECyanine7_TCR-VB131_Antibody_1_111623
    Human peripheral blood lymphocytes were stained with CD3 APC and with the anti-TCR Vß13.1 (clone H131) PE/Cyanine7 (left) or PE/Cyanine7 mouse IgG2b, κ isotype control (right). Data shown was gated on the lymphocyte population.
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
362405 25 tests $153
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362406 100 tests $370
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Description

TCR Vβ13.1 is a variant of the TCR β chain. The receptor is complexed with the TCR α chain and belongs to the immunoglobulin superfamily. It is expressed on a subset of T cells and some T cell clones. Variability in the β chain is generated by Vβ, Dβ, and Jβ gene rearrangement, while variability in the α chain is generated by Vα and Jα rearrangement. TCR Vβ13.1 has been shown to be related to antigen recognition and inflammation as well as diseases, such as HIV and multiple sclerosis.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse T cell hybridoma
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats of this clone) include: activation of TCR Vβ13.1 expressing cells1.

Application References

(PubMed link indicates BioLegend citation)
  1. Choi YW, et al. 1991. Proc. Natl. Acad. Sci. USA 88:8357.
RRID
AB_2721345 (BioLegend Cat. No. 362405)
AB_2721345 (BioLegend Cat. No. 362406)

Antigen Details

Structure
Immunoglobulin superfamily
Distribution

Subset of T cells

Function
Antigen recognition, activation of TCR Vβ13.1 bearing T cells
Ligand/Receptor
Peptide bound MHC molecules
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Hong J, et al. 1999. J. Immunol. 163:3530.
2. Jason J, et al. 1997. Scand. J. Immunol. 45:81.
3. Chang JC, et al. 1995. Ann. NY. Acad. Sci. 756:370.
4. Miyahara E, et al. 1999. Anticancer Res. 19:2057.
5. Usuku K, et al. 1993. Immunogenetics. 38:193.
6. Bakakos P, et al. 2002. Clin. Exp. Immunol. 129:370.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vbeta13.1 on UniProt.org
Go To Top Version: 1    Revision Date: 10/31/2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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