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PE/Cyanine7 anti-mouse LIFR Antibody

Pricing & Availability
Clone
W16163A (See other available formats)
Regulatory Status
RUO
Other Names
Leukemia inhibitory factor receptor alpha, Leukemia inhibitory factor receptor, Lifr, LIFR-a
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
W16163A_PECyanine7_LIFR_Antibody_053122_Updated
C57BL/6 mouse bone marrow cells were stained with anti-mouse Ly-6C FITC and anti-mouse LIFR (clone W16163A) PE/Cyanine7 (left) or rat IgG2b, κ PE/Cyanine7 isotype control (right).
  • W16163A_PECyanine7_LIFR_Antibody_053122_Updated
    C57BL/6 mouse bone marrow cells were stained with anti-mouse Ly-6C FITC and anti-mouse LIFR (clone W16163A) PE/Cyanine7 (left) or rat IgG2b, κ PE/Cyanine7 isotype control (right).
Compare all formats See PE/Cyanine7 spectral data
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158903 25 µg $183
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158904 100 µg $452
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Description

Leukemia inhibitory factor (LIFR) receptor alpha belongs to the type I cytokine receptor family, combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of LIF, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in theadult and the embryo.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse LIFR
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

W16163A can be used for surface staining of LIFR expressed on mouse splenocytes and bone marrow cells (tested on C57BL/6).

RRID
AB_2922491 (BioLegend Cat. No. 158903)
AB_2922491 (BioLegend Cat. No. 158904)

Antigen Details

Distribution

IFNAR+ pDCs, IFNAR+ lymphocytes, and Ly6C+ lymphocytes. Dim expression by CD11b+ and CD90.2+ lymphocytes.

Ligand/Receptor
LIFR combines with gp130 to form a receptor complex that mediates the action of LIF
Cell Type
Macrophages, Monocytes
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
  1. Wang T, et al. 2019. Mol Med Rep. 19:4719-26.
  2. Cheng L, et al. 1994. Development. 120:3145-3513.
  3. Mikelonis D, et al. 2014. Orphanet Journal of Rare Diseases. 9:34.
Gene ID
16880 View all products for this Gene ID
UniProt
View information about LIFR on UniProt.org
Go To Top Version: 1    Revision Date: 05/31/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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