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- Clone
- K21 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Blood group antigen precursor, type 1 (BG1)
- Isotype
- Mouse IgM, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Staining of BG1 (clone K21) on formalin-fixed paraffin embedded human kidney tumor tissue.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 932101 | 25 µg | $118 | ||||
| 932102 | 100 µg | $288 | ||||
BG1 is the precursor molecule for major blood group antigens, including the ABO and Lewis blood groups.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Tera-1 teratocarcinoma cell line.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunohistochemistry. For immunohistochemistry, a concentration range of 0.5 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
Tissue Sections: Formalin-fixed, paraffin-embedded tissues, and frozen tissues.
Pre-treatment: Not required.
Incubation: 20-60 minutes at room temperature.
Positive Control: Human kidney tumor tissue. - Application Notes
-
Clone K21 is specific for the Lacto-N-tetraose carbohydrate moiety.
We recommend using our Ultra Streptavidin (USA) HRP Detection Kit (Multi-Species) (Cat. No. 929601). -
Application References
(PubMed link indicates BioLegend citation) -
- Bry L, et al. 1996. Proc. Natl. Acad. Sci. USA 93:1161. (IHC)
- Domino S, et al. 2001. Mol. Cell Biol. 21:8336. (IHC) PubMed
- Product Citations
-
- RRID
-
AB_2566098 (BioLegend Cat. No. 932101)
AB_2566098 (BioLegend Cat. No. 932102)
Antigen Details
- Structure
- Lacto-N-tetraose carbohydrate moiety.
- Distribution
-
Widely expressed on red blood cells, epithelial tumors, teratocarcinoma, and renal-cell carcinoma.
- Function
- BG1 is the substrate for the ABO blood group-related antigens.
- Biology Area
- Cancer Biomarkers, Cell Biology, Neuroinflammation, Neuroscience
- Antigen References
-
1. Franchini M and Liumbruno GM. 2013. Clin. Chem. Lab. Med. 51(8):1545.
- Gene ID
- NA
- UniProt
- View information about BG1 on UniProt.org
Related FAQs
Other Formats
View All BG1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-Blood Group Antigen Precursor (BG1) | K21 | IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-Blood Group Antigen Precursor (BG1)
Staining of BG1 (clone K21) on formalin-fixed paraffin embed...
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