- Clone
- B72.3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- BRST3
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
915206 | 100 µg | $229 |
BRST-3, also known as TAG-72 (Tumor Associated Glycoprotein-72), a high molecular weight (220-400 kD) glycoprotein complex, is expressed by a wide variety of human adenocarcinomas.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against a membrane-enriched fraction of a breast carcinoma metastatic to the liver.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
B72.3 is reactive with a broad spectrum of epithelial malignancies in human, including invasive ductal carcinoma, lung carcinomas, ovarian, gastric and colonic adenocarcinomas. It appears to be non-reactive or weakly reactive to most normal tissues.
-
Application References
(PubMed link indicates BioLegend citation) -
- Liu G, et al. 2008. Eur. J. Nucl. Med. Mol. Imaging 35(2):272.
- Lyda MH, et al. 2000. Hum. Pathol. 31(8):980.
- Clemo FA, et al. 1995. Vet. Pathol. 32:147. (IHC)
- Colcher D, et al. 1981. Proc. Natl. Acad. Sci. USA 78:3199.
- RRID
-
AB_2616965 (BioLegend Cat. No. 915206)
Antigen Details
- Biology Area
- Cancer Biomarkers, Cell Biology
- Gene ID
- NA
- UniProt
- View information about BRST-3 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All BRST-3 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-BRST-3 | B72.3 | IHC-P |
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