- Clone
- 3G6 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Histone deacetylase 3, SMAP45, RPD3-2
- Previously
-
Covance Catalog# MMS-5073
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
815301 | 100 µL | $275 |
HDAC-3, also known as RPD3-2 and SMAP45, is a histone deacetylase and is responsible for the deacetylation of lysine residues on core histones and other histone substrates. The deacetylation of histones is important for transcriptional regulation, cell cycle progression, and other developmental related functions. HDAC-3 represses gene expression by participating in the transcriptional repressor activity of BCL6, by deacetylating H3K27 on enhancer elements. It is also thought to participate in transcriptional regulation through binding to YY1, a zinc-finger transcription factor.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a peptide sequence derived from the C-terminus of the human HDAC3 protein.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This antibody is effective in formalin-fixed paraffin-embedded immunohistochemical staining (IHC-P).
- RRID
-
AB_2564791 (BioLegend Cat. No. 815301)
Antigen Details
- Biology Area
- Cell Biology, Neuroscience
- Gene ID
- 8841 View all products for this Gene ID
- UniProt
- View information about HDAC3 on UniProt.org
Related FAQs
Other Formats
View All HDAC3 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-HDAC3 | 3G6 | IHC-P |
Compare Data Across All Formats
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Purified anti-HDAC3
IHC staining of purified anti-HDAC3 antibody (clone 3G6) on ...
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