- Clone
- W22039A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Intercellular Adhesion Molecule-2, ICAM-2
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
315405 | 100 µg | $102 |
CD102, also known as Intercellular Adhesion Molecule-2, or ICAM-2, is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN, and MAC-1.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD102 (ICAM-2) recombinant protein fragment
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Flow cytometry testing showed that clone W22039A does not affect the binding of clones W22038F and CBR-IC2/2 on target cells.
Antigen Details
- Structure
- 55 kD type I transmembrane glycoprotein, Ig superfamily
- Distribution
-
Vascular endothelial cells, lymphocytes, monocytes, platelets
- Function
- Adhesion, costimulation
- Ligand/Receptor
- LFA-1, DC-SIGN, MAC-1
- Cell Type
- Epithelial cells, Lymphocytes, Monocytes, Platelets
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Weber KSC, et al. 2004. Inflammation. 28:177-88.
- Barclay A, et al. 1997. The Leukoycte Antigen FactsbookAcademic Press.
- Casasnovas JM, et al. 1999. P Natl Acad Sci. USA. 96:3017.
- Diamonds MS, et al. 1990. J Cell Biol. 111:3129-39.
- Gene ID
- 3384 View all products for this Gene ID
- UniProt
- View information about CD102 on UniProt.org
Related FAQs
Other Formats
View All CD102 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD102 (ICAM-2) | W22039A | FC |
Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD102 (ICAM-2)
Human peripheral blood leukocytes were stained with purified...
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