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- Clone
- W22038F (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Intercellular Adhesion Molecule-2, ICAM-2
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood leukocytes were stained with purified anti-human CD102 (ICAM-2) (clone W22038F) (left) or purified rat IgG2a, κ isotype control (right), followed by anti-rat IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 315905 | 100 µg | $102 | ||||
CD102, also known as Intercellular Adhesion Molecule-2, or ICAM-2, is a 55 kD type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune responses. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN, and MAC-1.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Human CD102 (ICAM-2) recombinant protein fragment
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Flow cytometry testing showed that clone W22038F can block the binding of clone CBR-IC2/2 on target cells.
Flow cytometry testing showed that clone W22038F does not affect the binding of clone W22039A on target cells.
Antigen Details
- Structure
- 55 kD type I transmembrane glycoprotein, Ig superfamily
- Distribution
-
Vascular endothelial cells, lymphocytes, monocytes, platelets
- Function
- Adhesion, costimulation
- Ligand/Receptor
- LFA-1, DC-SIGN, MAC-1
- Cell Type
- Epithelial cells, Lymphocytes, Monocytes, Platelets
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
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- Weber KSC, et al. 2004. Inflammation. 28:177-88.
- Barclay A, et al. 1997. The Leukoycte Antigen FactsbookAcademic Press.
- Casasnovas JM, et al. 1999. P Natl Acad Sci. USA. 96:3017.
- Diamonds MS, et al. 1990. J Cell Biol. 111:3129-39.
- Gene ID
- 3384 View all products for this Gene ID
- UniProt
- View information about CD102 on UniProt.org
Other Formats
View All CD102 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD102 (ICAM-2) | W22038F | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD102 (ICAM-2)
Human peripheral blood leukocytes were stained with purified...
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