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- Clone
- A17193B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD6 ligand, Activated Leukocyte Cell Adhesion Molecule (ALCAM)
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with anti-human CD3 APC and purified anti-human CD166 (clone A17193B) or purified mouse IgG2b, κ followed by PE goat anti-mouse IgG.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 381902 | 100 µg | $141 | ||||
CD166, also known as the CD6 ligand or the Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a 100-105 kD transmembrane glycoprotein. It belongs to the Ig superfamily of proteins and expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development. Recently, CD166 has also been used as a potential cancer stem cell marker.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD166 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
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AB_2936519 (BioLegend Cat. No. 381902)
Antigen Details
- Structure
- Type I transmembrane glycoprotein belonging to the Ig superfamily of proteins
- Distribution
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CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons
- Function
- Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development
- Ligand/Receptor
- CD6
- Cell Type
- Granulocytes, Monocytes, T cells
- Biology Area
- Cell Adhesion, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
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- Aruffo A, et al. 1997. Immunol Today. 18:498-504.
- Bowen MA, et al. 1995. J Exp Med. 181:2213-20.
- Patel DD, et al. 1995. J Exp Med. 181:1563-8.
- Horst D, et al. 2009. Cancer Invest. 27:844-50.
- Gene ID
- 214 View all products for this Gene ID
- UniProt
- View information about CD166 on UniProt.org
Related FAQs
Other Formats
View All CD166 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD166 | A17193B | FC |
| PE anti-human CD166 | A17193B | FC |
| APC anti-human CD166 | A17193B | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD166
Human peripheral blood lymphocytes were stained with anti-hu... -
PE anti-human CD166
Human peripheral blood lymphocytes were stained with anti-hu... -
APC anti-human CD166
Human peripheral blood lymphocytes were stained with anti-hu...
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