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- Clone
- HSL96 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- VpreB, VPREB1, IGVPB
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human pre-B cell line NALM6 stained with HSL96 PE
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 347402 | 100 µg | $265 | ||||
CD179a is an 18 kD Ig V-like protein expressed on pro-B and early pre-B cells. It is a member of the Ig gene superfamily, known as VpreB, VPREB1, and IGVPB. CD179a noncovalently associates with CD179b (λ5) to form a surrogate light (SL) chain. The SL chain is complexed with membrane bound IgM heavy (µH) chain and CD79a/CD79b heterodimer to form the pre-B-cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation though it has been reported that the pre-BCR complex plays a critical role in B cell development.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Tsyganezawa K, et al. 1998. Blood 92:4317
- Kiyokawa N, et al. 2004. Modern Pathology. 17:423
- RRID
-
AB_2241746 (BioLegend Cat. No. 347402)
Antigen Details
- Structure
- Ig superfamily, Ig V-like, 18 kD, noncovalently associates with CD179b to form surrogate light (SL) chain
- Distribution
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Pro-B and early Pre-B cells
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
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1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication
2. Zhang M, et al. 2004. Cell. Mol. Immunol. 1:89 - Gene ID
- 7441 View all products for this Gene ID
- UniProt
- View information about CD179a on UniProt.org
Other Formats
View All CD179a Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD179a (VpreB) | HSL96 | FC,IP |
| PE anti-human CD179a (VpreB) | HSL96 | FC |
| TotalSeq™-A0934 anti-human CD179a (VpreB) | HSL96 | PG |
| Brilliant Violet 421™ anti-human CD179a (VpreB) | HSL96 | FC |
| TotalSeq™-B0934 anti-human CD179a (VpreB) | HSL96 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD179a (VpreB)
Human pre-B cell line NALM6 stained with HSL96 PE -
PE anti-human CD179a (VpreB)
Human pre-B cell line NALM6 stained with HSL96 PE -
TotalSeq™-A0934 anti-human CD179a (VpreB)
-
Brilliant Violet 421™ anti-human CD179a (VpreB)
Human pre-B cell line NALM6 was stained with anti-human CD17... -
TotalSeq™-B0934 anti-human CD179a (VpreB)
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