- Clone
- QA19A08 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, Glycophorin A, MNS blood group, GYPA
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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379002 | 100 µg | $101 |
CD235a (Glycophorin A) is member of the glycophorin A family. It is a type I sialoglycoprotein with a molecular weight of 10 kD, present in the cell membrane as a homodimer. Glycophorin A is expressed by erythroid precursors and erythrocytes. It carries the antigen determinants for the MNS blood groups and has been proposed to be an inhibitor of hemagglutination and hemolysis. Glycophorin A binds siglec 5, the erythrocyte binding antigen (EBA-175) of P. falciparum and some viruses, including influenza virus and hepatitis A virus.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2927846 (BioLegend Cat. No. 379002)
Antigen Details
- Structure
- Member of the glycophorin A family; type I protein with a molecular weight of 10 kD; present in the membrane as homodimer
- Distribution
-
Erythrocytes and erythroid precursors
- Function
- Possible inhibitor of hemagglutination and hemolysis; carries the antigen determinants for the MNS blood groups
- Ligand/Receptor
- Siglec 5, erythrocyte binding antigen (EBA-175) of P. falciparum, receptor for the influenza virus, hepatitis A virus
- Antigen References
-
- Reid ME. 2009. Immunohematology. 25:95-101.
- Palacajornsuk P. 2006. Immunohematology. 22:171-82.
- Pasvol G. 2003. Trends Parasitol. 19:430-2.
- Takakuwa Y. 2001. Curr Opin Hematol. 8:80-4.
- Gene ID
- 2993 View all products for this Gene ID
- UniProt
- View information about CD235a on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD235a (Glycophorin A) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD235a (Glycophorin A) Recombinant Antibody | QA19A08 | FC |
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Purified anti-human CD235a (Glycophorin A) Recombinant Antibody
Human red blood cells were stained with purified anti-human ...
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