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- Clone
- DY12 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- P220/240, DY12, DY35
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes stained with purified DY12, followed by biotinylated anti-mouse IgG and Sav-PE
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 334402 | 100 µg | $129 | ||||
CD245 is a 220-250 kD transmembrane glycoprotein, also known as p220/240, DY12 or DY35. It is expressed on peripheral blood lymphocytes, monocytes, granulocytes, and platelets. The expression level of CD245 on lymphocytes can be upregulated after 3-7 days stimulation with PHA. It has been reported that CD245 is involved in signal transduction and costimulation of T and NK cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_1186022 (BioLegend Cat. No. 334402)
Antigen Details
- Distribution
-
Blood lymphocytes, monocytes and granulocytes
- Function
- Signal transduction and costimulation
- Cell Type
- Granulocytes, Lymphocytes, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
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1. H. Zola et al. Eds. 2007. Leukocyte and Stromal Cell Molecule:The CD Markers. WILEY-LISS:A John Wiley & Sons Inc, Publication
- Gene ID
- 4863 View all products for this Gene ID
- UniProt
- View information about CD245 on UniProt.org
Other Formats
View All CD245 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD245 (p220/240) | DY12 | FC |
| PE anti-human CD245 (p220/240) | DY12 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD245 (p220/240)
Human peripheral blood lymphocytes stained with purified DY1... -
PE anti-human CD245 (p220/240)
Human peripheral blood granulocytes stained with DY12 PE
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