- Clone
- LN1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), B cell antigen CD75
- Isotype
- Mouse IgM, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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326901 | 25 µg | $71 |
CD75 is a 43-85 kD type II transmembrane sialyltransferase protein, also known as beta-galactoside alpha-2,6-sialyltransferase. It is a member of glycosyltransferase family that transfers sialic acid from a donor substrate (CMP-sialic acid) to terminal galactose on glycan chains. CD75 is predominately expressed on germinal center originated B cells and lymphomas. It is also found on mature sIg+ B cells and epithelial cells of lung, breast, kidney, and prostate.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human PBL nuclei
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-P, IHC-F, WB - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported applications (for the relevant formats) include: immunohistochemical staining1,2 of frozen sections and formalin-fixed paraffin-embedded sections, and Western blotting3.
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Application References
(PubMed link indicates BioLegend citation) -
- Epstein AL, et al.1984. J. Immunol. 133:1028. (IHC)
- Marder RJ, et al. 1985. Lab. Invest. 52:497. (IHC)
- Kramer G, et al. 2004. BJU Int. 93:822. (WB)
- Product Citations
-
- RRID
-
AB_2194435 (BioLegend Cat. No. 326901)
Antigen Details
- Structure
- 43-85 kD type II transmembrane sialoprotein, glycosyltransferase family
- Distribution
-
Germinal center derived B cells, epithelial cells
- Cell Type
- B cells, Epithelial cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Epstein AL, et al. 1984. J. Immunol. 133:1028.
2. Kramer G, et al. 2004. BJU Int. 93:822.
3. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication - Gene ID
- 6480 View all products for this Gene ID
- UniProt
- View information about CD75 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD75 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD75 | LN1 | FC,IHC-P,IHC-F,WB |
Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD75
Human peripheral blood lymphocytes stained with purified LN1...
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