- Clone
- CD84.1.21 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Ly9b, SLAMF5, GR6
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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326002 | 100 µg | $129 |
CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of (preferentially on CD45RO+) T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. The antibody CD84.1.21 is able to enhance CD3 induced IFN-γ production and partially block CD84-Ig binding to lymphocytes.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- 300.19 cell line transfected with the CD84 full-length DNA
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional reported (for the relevant formats) applications include: immunoprecipitation2, and enhancing CD3 induced IFN-? production1 and partially block CD84-Ig binding to lymphocytes1.
-
Application References
(PubMed link indicates BioLegend citation) -
- Martin M, et al. 2001. J. Immunol. 167:3668.
- Sayós J, et al. 2001. Blood 97:3867.
- Morra M, et al. 2001. EMBO 20:5840.
- Morra M, 2001. J. Biol. Chem. 276:36809.
- Romero X, et al. 2004. Tissue Antigens 64:132.
- Product Citations
-
- RRID
-
AB_830813 (BioLegend Cat. No. 326002)
Antigen Details
- Structure
- 64-82 kD glycoprotein, CD2 subset of Ig superfamily, SLAM family
- Distribution
-
B cells, monocytes, thymocytes, platelets, subset of (preferentially on CD45RO+) T cells
- Function
- Homophilic adhesion, T cell activation
- Ligand/Receptor
- CD84
- Cell Type
- B cells, Monocytes, Platelets, T cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. de la Fuente MA, et al. 1997. Blood 90 (6):2398.
2. Tangye SG, et al. 2002. Eur. J. Immunol. 32(6):1640.
3. Tangye SG, et al. 2003. J. Immunol. 171:2485.
4. Martin M, et al. 2001. J. Immunol. 167:3668. - Gene ID
- 8832 View all products for this Gene ID
- UniProt
- View information about CD84 on UniProt.org
Related FAQs
Other Formats
View All CD84 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD84 | CD84.1.21 | FC,IP |
PE anti-human CD84 | CD84.1.21 | FC |
APC anti-human CD84 | CD84.1.21 | FC |
TotalSeq™-A0872 anti-human CD84 | CD84.1.21 | PG |
TotalSeq™-C0872 anti-human CD84 Antibody | CD84.1.21 | PG |
TotalSeq™-B0872 anti-human CD84 | CD84.1.21 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD84
Human peripheral blood lymphocytes stained with purified CD8... -
PE anti-human CD84
Human peripheral blood lymphocytes were stained with CD45RO ... -
APC anti-human CD84
Human peripheral blood lymphocytes were stained with CD45RO ... -
TotalSeq™-A0872 anti-human CD84
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TotalSeq™-C0872 anti-human CD84 Antibody
-
TotalSeq™-B0872 anti-human CD84
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