- Clone
- QA20A13 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Latency Ikaros family zinc finger protein 4 (IKZF4), ZMFN1A4, KIAA1782
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
384002 | 100 µg | $299 |
EOS, also known as IKZF4, is an IKAROS Family Member expressed in lymphocytes, specifically in Tregs. It plays an important role in the inhibitory function of Tregs. It may be involved in the development of the central and peripheral nervous systems as well as lymphoid development.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2936577 (BioLegend Cat. No. 384002)
Antigen Details
- Structure
- IKAROS family member
- Distribution
-
Lymphocytes, specifically in Tregs
- Function
- Essential for inhibitory function of Tregs
- Interaction
- Binds to 5'GGGAATRCC-3' Ikaros-binding sequence
- Antigen References
-
- Honma Y, et al. 1999. FEBS Lett. 447:76-80.
- Perdomo J, et al. 2000. J Biol Chem. 275:38347-54.
- Westman BJ, et al. 2004. Biochemistry. 43:13318-27.
- Pan F, et al. 2009. Science. 10.1126/science.1176077.
- Gene ID
- 64375 View all products for this Gene ID
- UniProt
- View information about EOS on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All EOS Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human EOS Recombinant Antibody | QA20A13 | FC |
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Purified anti-human EOS Recombinant Antibody
Human peripheral blood lymphocytes were surface stained with...
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