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- Clone
- S18011E (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9Rα
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse splenocytes were cultured with anti-mouse CD40 antibody for four days. Cells were stained with purified CD129 (clone S18011E) (left) or purified rat IgG2a, κ isotype (right), followed by anti-rat IgG APC and CD19 PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 158702 | 500 µg | $581 | ||||
CD129 is the ligand binding subunit of IL-9 receptor (IL-9R or IL-9Rα). It is a type I transmembrance glycoprotein belonging to the hematopoientin receptor superfamily. The signal transducing subunit is common gamma chain (γc, CD132), which is shared with receptors for IL-2, IL-4, IL-7, and IL-21. The mouse IL-9R has 468aa and is about 52.2kD. Besides modulating immune response, signals through IL-9 and IL-9R are also invoved in allergy and inflammatory disorders.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse IL-9R transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
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AB_2832563 (BioLegend Cat. No. 158702)
Antigen Details
- Structure
- Type I transmemberane glycoprotein; WSXWS motif
- Distribution
-
Subset of B cells, mast cells
- Function
- Binding IL-9; activate JAK-STAT signaling
- Interaction
- Common gamma chain (CD132)
- Ligand/Receptor
- IL-9
- Cell Type
- B cells, Eosinophils, Mast cells, T cells, Thymocytes
- Biology Area
- Adaptive Immunity, Immuno-Oncology, Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, Growth Factors
- Antigen References
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- Druez C, et al. 1990. J Immunol. 145:2494-9.
- Renauld JC, et al. 1992. Proc Natl Acad Sci USA. 89:5690-4.
- Takatsuka S, et al. 2018. Nat Immunol. 19:1025-1034.
- Gene ID
- 16199 View all products for this Gene ID
- UniProt
- View information about CD129 on UniProt.org
Related FAQs
Other Formats
View All CD129 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| APC anti-mouse CD129 (IL-9R) | S18011E | FC |
| PE anti-mouse CD129 (IL-9R) | S18011E | FC |
| Purified anti-mouse CD129 (IL-9R) | S18011E | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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APC anti-mouse CD129 (IL-9R)
C57BL/6 mouse splenocytes were cultured with anti-mouse CD40... -
PE anti-mouse CD129 (IL-9R)
C57BL/6 mouse splenocytes were cultured with anti-mouse CD40... -
Purified anti-mouse CD129 (IL-9R)
C57BL/6 mouse splenocytes were cultured with anti-mouse CD40...
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