Purified anti-mouse CD7 Antibody

Pricing & Availability
Clone
S23010B (See other available formats)
Regulatory Status
RUO
Isotype
Rat IgG1, κ
Ave. Rating
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Product Citations
publications
S23010B_PURE_CD7_FC_1_100124
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 (clone 17A2) APC and purified anti-mouse CD7 (clone S23010B (left) or purified rat IgG1, κ isotype control (right) followed by anti-rat IgG1 PE.
  • S23010B_PURE_CD7_FC_1_100124
    C57BL/6 mouse splenocytes were stained with anti-mouse CD3 (clone 17A2) APC and purified anti-mouse CD7 (clone S23010B (left) or purified rat IgG1, κ isotype control (right) followed by anti-rat IgG1 PE.
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167102 100 µg $380
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Description

CD7, also known as Leu-9, is an approximately 40 kD glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily. The extracellular domain of mature mouse CD7 shares 43% and 81% amino acid sequence similarity with human and rat CD7, respectively.  Mouse CD7 mRNA has been found in thymus, spleen, bone marrow, and small intestine. Both the ligand and function of mouse CD7 are not yet clear.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD7-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Antigen Details

Structure
Type I transmembrane glycoprotein; Ig superfamily
Distribution

Mouse CD7 mRNA exists in thymus, spleen, bone marrow, and small intestine

Cell Type
Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Yoshikawa K, et al. 1993. Immunogenetics. 37:114-9.
  2. Haynes BF, et al. 1999. Crit Rev Immunol. 19:331.
  3. Bonilla FA, et al. 1997. Int Immunol. 9:1875.
Gene ID
12516 View all products for this Gene ID
UniProt
View information about CD7 on UniProt.org
Go To Top Version: 1    Revision Date: 10/01/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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