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- Clone
- QA19A88 (See other available formats)
- Regulatory Status
- RUO
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 FITC and purified anti-mouse TCR Vβ13 recombinant (clone QA19A88) (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG1 PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 104202 | 100 µg | $112 | ||||
Vβ13 T cell receptor (TCR Vβ13) is a variant of TCR β chain that along with TCR α chain forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition in the MHC-Peptide complex and initiation of T cell-mediated immune responses. The most frequently β chains found in the immune response to myelin basic protein (MBP) in B10.PL mice are Vβ13 and Vβ8.2.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2922455 (BioLegend Cat. No. 104202)
Antigen Details
- Structure
- Member of the immunoglobulin superfamily, Vβ13 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer
- Distribution
-
Expressed on a subset of TCR αβ+ T cells
- Function
- Recognition of peptides presented by the MHC molecules, responsible for T cell mediated immune responses
- Ligand/Receptor
- MHC-Peptide complex
- Cell Type
- T cells, Th1, Th17
- Biology Area
- Immunology
- Molecular Family
- TCRs
- Antigen References
-
- Zaller DM, et al. 1990. J Exp Med. 171:1943-55.
- Gentile F, et al. 2004. Immunology. 112:13-25.
- Lode HN, et al. 1999. Proc Natl Acad Sci U S A. 96:8591-6.
- Gene ID
- 21577 View all products for this Gene ID
- UniProt
- View information about TCR Vbeta13 on UniProt.org
Related FAQs
Other Formats
View All TCR Vβ13 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-mouse TCR Vβ13 Recombinant Antibody | QA19A88 | FC |
| Purified anti-mouse TCR Vβ13 Recombinant Antibody | QA19A88 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-mouse TCR Vβ13 Recombinant Antibody
C57BL/6 mouse splenocytes were stained with CD3 FITC and ant... -
Purified anti-mouse TCR Vβ13 Recombinant Antibody
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 F...
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