Login/Register 
United States ($) USD
Austria (€) EUR
Belgium (€) EUR
Finland (€) EUR
France (€) EUR
Germany (€) EUR
Ireland (€) EUR
Japan (¥) JPY
Luxembourg (€) EUR
Netherlands (€) EUR
Switzerland (CHF) CHF
United Kingdom (£) GBP
- Clone
- S19013C (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Unc-93 homolog B1, TLR signaling regulator
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 splenocytes were surface stained with CD11b Alexa Fluor® 647 and then treated with True-Nuclear™ Transcription Factor Buffer Set. Cells were then stained with UNC93B1 (clone S19013C) purified (left) or rat IgG2a, κ purified isotype control (right), followed by anti-rat IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 162802 | 100 µg | $347 | ||||
Unc93b1 is a 12 pass transmembrane protein highly conserved in the endoplasmic reticulum (ER). Unc93b1 plays a role in the transport of TLRs from the ER to the cell surface or endosomes where they can engage pathogens nucleotides and trigger signaling cascades. Mutations in the Unc93b1 gene have shown to cause susceptibility to some common infections (HSV hypersensitivity in humans, and mouse cytomegalovirus).
Product Details
Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse UNC93B1-transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICFC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. - RRID
-
AB_2888873 (BioLegend Cat. No. 162802)
Antigen Details
- Structure
- 12 pass transmembrane protein
- Antigen References
-
1. Majer. et al. 2019. Nature. 575, 371–374
2. Pelka et al. 2018. Immunity. 48, 911–922
3. Huh et al. 2014. PNAS. 111, 7072–7077 - Gene ID
- 81622 View all products for this Gene ID
- UniProt
- View information about UNC93B1 on UniProt.org
Other Formats
View All UNC93B1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse UNC93B1 Antibody | S19013C | ICFC |
| PE anti-mouse UNC93B1 Antibody | S19013C | ICFC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse UNC93B1 Antibody
C57BL/6 splenocytes were surface stained with CD11b Alexa Fl... -
PE anti-mouse UNC93B1 Antibody
C57BL/6 splenocytes were surface stained with CD11b Alexa Fl...
Follow Us