- Clone
- 2B12 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CAS, p120, CTNND, P120CAS, P120CTN, p120(CAS), p120(CTN), catenin delta-1
- Previously
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Covance Catalog# MMS-5040
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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828301 | 100 µL | $275 |
p120/Catenin delta-1 (CTNND1) is a membrane protein that binds to cadherins and participates in signal transduction. It is the prototypic member of a growing subfamily of Armadillo-domain proteins found at cell-cell junctions and in nuclei. Known to bind specifically to presenilin 1, it regulates the maintenance of dendrites and dendritic spines in mature cortex.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against tyrosine phosphoproteins purified from chicken embryonic fibroblasts (CEFs) expressing pp60/c-src 527F and 2A/527F.
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
- Application
-
WB - Quality tested
IP - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Kanner S., et al. Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. Mol Cell Bio, 11(2): 713-720, February 1991.
- Kanner S., et al. Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases. Proc Natl Acad Sci U.S.A., 87(9): 3328-3332, May 1990.
- Staddon JM, et al. 1995. J. Cell. Biol. 130:369. (WB, IP)
- Kim L and Wong TW, et al. 1995. Mol. Cell. Biol. 15:4553. (WB, IP)
- Product Citations
-
- RRID
-
AB_2564919 (BioLegend Cat. No. 828301)
Antigen Details
- Structure
- Expected MW: 115 kD
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules
- Gene ID
- 1500 View all products for this Gene ID
- UniProt
- View information about p120 Catenin on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All p120 Catenin Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-p120 Catenin | 2B12 | WB,IP |
Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-p120 Catenin
Western blot of purified anti-p120 Catenin antibody (clone 2...
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