- Clone
- 76-2-11 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD8a, Leu2 T-lymphocyte antigen, LEU2, MAL, T8, CD8α
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
251202 | 100 µg | $160 |
CD8 is a 35 kD type I transmembrane glycoprotein and is expressed as either a CD8αα homodimer or a CD8αβ heterodimer. It functions as a MHC Class I co-receptor for antigen recognition. It is highly expressed in thymocytes, cytotoxic T-cells, and NK cells.
Product DetailsProduct Details
- Verified Reactivity
- Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2924499 (BioLegend Cat. No. 251202)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, expressed as CD8αα homodimer or a CD8αβ heterodimer
- Distribution
-
Thymocytes, suppressor/cytotoxic subpopulation of peripheral T cells
- Function
- Co-receptor, stabilizes MHC Class I-TCR interaction
- Ligand/Receptor
- T-cell receptors, MHC-I
- Cell Type
- NK cells, T cells, Thymocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Wang W, et al. 2015. Mol Genet Genomics. 290:1447-56.
- Gene ID
- 396627 View all products for this Gene ID
- UniProt
- View information about CD8 on UniProt.org
Related FAQs
Other Formats
View All CD8 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-pig CD8 | 76-2-11 | FC |
PE anti-pig CD8 | 76-2-11 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-pig CD8
Porcine peripheral blood lymphocytes were stained with anti-... -
PE anti-pig CD8
Porcine peripheral blood lymphocytes were stained with anti-...
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