- Clone
- OX-108 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD200R1, MOX2R, Orexin Receptor 2 (OX2R), CD200 Receptor
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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329315 | 100 µg | $83 | ||||
329316 | 1 mg | $440 |
Select size of product is eligible for a 40% discount! Promotion valid until December 31, 2024. Exclusions apply. To view full promotion terms and conditions or to contact your local BioLegend representative to receive a quote, visit our webpage.
CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils, but also by other leukocytes including T cells and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissues.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD200R full length fusion protein
- Formulation
- 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
- Endotoxin Level
- Less than 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
Blocking - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2 µg per 106 cells in 100 µL volume or 100 µL of whole blood. For blocking application, the ND50 range: 0.05 - 0.4 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Wright GJ, et al. 2003. J. Immunol. 171:3034.
- RRID
-
AB_2860859 (BioLegend Cat. No. 329315)
AB_2860859 (BioLegend Cat. No. 329316)
Antigen Details
- Structure
- Immunoglobulin superfamily glycoprotein.
- Distribution
-
Monocytes, neutrophils, T cells, mast cells.
- Ligand/Receptor
- CD200, OX2.
- Cell Type
- Mast cells, Monocytes, Neutrophils, T cells
- Biology Area
- Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Wright GJ, et al. 2003. J. Immunol. 171:3034.
2. Gorczynski R, et al. 2004. J. Immunol. 172:7744. - Gene ID
- 131450 View all products for this Gene ID
- UniProt
- View information about CD200R on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- Do you guarantee that your antibodies are totally pathogen free?
-
BioLegend does not test for pathogens in-house aside from the GoInVivo™ product line. However, upon request, this can be tested on a custom basis with an outside, independent laboratory.
- Does BioLegend test each Ultra-LEAF™ antibody by functional assay?
-
No, BioLegend does not test Ultra-LEAF™ antibodies by functional assays unless otherwise indicated. Due to the possible complexities and variations of uses of biofunctional antibodies in different assays and because of the large product portfolio, BioLegend does not currently perform functional assays as a routine QC for the antibodies. However, we do provide references in which the antibodies were used for functional assays and we do perform QC to verify the specificity and quality of the antibody based on our strict specification criteria.
- Does BioLegend test each Ultra-LEAF™ antibody for potential pathogens?
-
No, BioLegend does not test for pathogens in-house unless otherwise indicated. However, we can recommend an outside vendor to perform this testing as needed.
- Have you tested this Ultra-LEAF™ antibody for in vivo or in vitro applications?
-
We don't test our antibodies for in vivo or in vitro applications unless otherwise indicated. Depending on the product, the TDS may describe literature supporting usage of a particular product for bioassay. It may be best to further consult the literature to find clone specific information.
Other Formats
View All CD200R Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD200R | OX-108 | FC,ICC |
PE anti-human CD200R | OX-108 | FC |
APC anti-human CD200R | OX-108 | FC |
PE/Dazzle™ 594 anti-human CD200R | OX-108 | FC |
PE/Cyanine7 anti-human CD200R | OX-108 | FC |
Brilliant Violet 421™ anti-human CD200R | OX-108 | FC |
Ultra-LEAF™ Purified anti-human CD200R | OX-108 | FC,Block |
TotalSeq™-C1143 anti-human CD200R | OX-108 | PG |
TotalSeq™-B1143 anti-human CD200R | OX-108 | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD200R
Human peripheral blood lymphocytes were stained with CD200R ... -
PE anti-human CD200R
Human peripheral blood lymphocytes stained with CD3 (UCHT1) ... -
APC anti-human CD200R
Human peripheral blood lymphocytes were stained with CD3 Bri... -
PE/Dazzle™ 594 anti-human CD200R
Human perpipheral blood lymphocytes were stained with CD3 FI... -
PE/Cyanine7 anti-human CD200R
Human perpipheral blood lymphocytes were stained with CD3 (c... -
Brilliant Violet 421™ anti-human CD200R
Human perpipheral blood lymphocytes were stained with CD3 (c... -
Ultra-LEAF™ Purified anti-human CD200R
Recombinant biotinylated human CD200 (Black circles, Cat. No... -
TotalSeq™-C1143 anti-human CD200R
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TotalSeq™-B1143 anti-human CD200R
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