- Clone
- OX-110 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- OX-2R, Orexin Receptor 2 (OX2R), CD200R
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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123917 | 100 µg | $237 | ||||
123918 | 1 mg | $743 |
Select size of product is eligible for a 40% discount! Promotion valid until December 31, 2024. Exclusions apply. To view full promotion terms and conditions or to contact your local BioLegend representative to receive a quote, visit our webpage.
CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils but also by other leukocytes including T lymphocytes and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue. Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function. Levels of expression on resting peripheral blood cells are relatively low.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Fusion protein mouse CD200RCD4d3
- Formulation
- 0.2 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative.
- Endotoxin Level
- Less than 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
FA - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
Additional applications (for the relevant formats) include: in vivo studies3. The Ultra-LEAF™ purified antibody is recommended for functional assays.
-
Application References
(PubMed link indicates BioLegend citation) -
- Voulgaraki D, et al. 2005. Immunol. 115:337
- Stumper TL, et al. 2011. J. Immunol. 186:1970. PubMed
- Talebian F, et al. 2012. PLoS One 7:e31442. (FA)
- RRID
-
AB_2890680 (BioLegend Cat. No. 123917)
AB_2890680 (BioLegend Cat. No. 123918)
Antigen Details
- Distribution
-
Monocytes and neutrophils, T lymphocytes and mast cells
- Cell Type
- Mast cells, Monocytes, Neutrophils, T cells
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules
- Antigen References
-
1. Voulgaraki D, et al. 2005. Immunol. 115:337
- Gene ID
- 57781 View all products for this Gene ID
- UniProt
- View information about CD200R on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- Do you guarantee that your antibodies are totally pathogen free?
-
BioLegend does not test for pathogens in-house aside from the GoInVivo™ product line. However, upon request, this can be tested on a custom basis with an outside, independent laboratory.
- Does BioLegend test each Ultra-LEAF™ antibody by functional assay?
-
No, BioLegend does not test Ultra-LEAF™ antibodies by functional assays unless otherwise indicated. Due to the possible complexities and variations of uses of biofunctional antibodies in different assays and because of the large product portfolio, BioLegend does not currently perform functional assays as a routine QC for the antibodies. However, we do provide references in which the antibodies were used for functional assays and we do perform QC to verify the specificity and quality of the antibody based on our strict specification criteria.
- Does BioLegend test each Ultra-LEAF™ antibody for potential pathogens?
-
No, BioLegend does not test for pathogens in-house unless otherwise indicated. However, we can recommend an outside vendor to perform this testing as needed.
- Have you tested this Ultra-LEAF™ antibody for in vivo or in vitro applications?
-
We don't test our antibodies for in vivo or in vitro applications unless otherwise indicated. Depending on the product, the TDS may describe literature supporting usage of a particular product for bioassay. It may be best to further consult the literature to find clone specific information.
Other Formats
View All CD200R Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD200R (OX2R) | OX-110 | FC |
FITC anti-mouse CD200R (OX2R) | OX-110 | FC |
PE anti-mouse CD200R (OX2R) | OX-110 | FC |
TotalSeq™-A0807 anti-mouse CD200R (OX2R) | OX-110 | PG |
APC anti-mouse CD200R (OX2R) | OX-110 | FC |
TotalSeq™-C0807 anti-mouse CD200R (OX2R) | OX-110 | PG |
Ultra-LEAF™ Purified anti-mouse CD200R (OX2R) | OX-110 | FC,FA |
TotalSeq™-B0807 anti-mouse CD200R (OX2R) | OX-110 | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse CD200R (OX2R)
C57BL/6 mouse bone marrow cells were stained with purified C... -
FITC anti-mouse CD200R (OX2R)
C57BL/6 bone marrow cells stained with OX-110 FITC (gated on... -
PE anti-mouse CD200R (OX2R)
C57BL/6 bone marrow cells stained with OX-110 PE (gated on m... -
TotalSeq™-A0807 anti-mouse CD200R (OX2R)
-
APC anti-mouse CD200R (OX2R)
C57BL/6 mouse bone marrow cells were stained with CD200R (OX... -
TotalSeq™-C0807 anti-mouse CD200R (OX2R)
-
Ultra-LEAF™ Purified anti-mouse CD200R (OX2R)
C57BL/6 bone marrow cells were stained with Ultra-LEAF™ puri... -
TotalSeq™-B0807 anti-mouse CD200R (OX2R)
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