GMP FITC anti-human CD38 Antibody

Pricing & Availability
Clone
HIT2 (See other available formats)
Workshop
III 155
Other Names
T10, ADP-ribosyl cyclase
Isotype
Mouse IgG1, κ
HIT2_GMP_FITC_CD38_Antibody_082622
Typical results from human peripheral blood lymphocytes stained either with HIT2 FITC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
  • HIT2_GMP_FITC_CD38_Antibody_082622
    Typical results from human peripheral blood lymphocytes stained either with HIT2 FITC used at 5 µL/test (filled histogram) or with an isotype control (open histogram).
Compare all formats See GMP FITC spectral data
Cat # Size Price Quantity Check Availability
260148 100 tests $220.00
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Description

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA) and a stabilizer.
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
200 µg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6 and spatial biology (IBEX)10,11.

Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Dieu M. 1998. J. Exp. Med. 188:373.
  3. Esser M, et al. 2001. J. Virol. 75:6173.
  4. Jeannin P, et al. 1999. J. Immunol. 162:2044.
  5. Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
  6. van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
  7. Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
  8. Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
  9. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci USA. 117:33455-33465. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Disclaimer

GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include:

  • Batch-to-batch consistency
  • Material traceability
  • Documented procedures
  • Documented employee training
  • Equipment maintenance and monitoring records
  • Lot-specific certificates of analysis
  • Quality audits per ISO 13485:2016
  • QA review of released products

Antigen Details

Structure
ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
Distribution

T cells, B cells, NK, myeloid, plasma, and dendritic cells

Function
Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Dendritic cells, NK cells, Plasma cells, T cells
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.

Gene ID
952 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org

Other Formats

View All CD38 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-human CD38 HIT2 FC
FITC anti-human CD38 HIT2 FC
PE anti-human CD38 HIT2 FC
PE/Cyanine5 anti-human CD38 HIT2 FC
Purified anti-human CD38 HIT2 FC,CyTOF®,IHC-F
Alexa Fluor® 488 anti-human CD38 HIT2 FC
Alexa Fluor® 647 anti-human CD38 HIT2 FC
PE/Cyanine7 anti-human CD38 HIT2 FC
Biotin anti-human CD38 HIT2 FC
PerCP anti-human CD38 HIT2 FC
PerCP/Cyanine5.5 anti-human CD38 HIT2 FC
Alexa Fluor® 700 anti-human CD38 HIT2 FC,SB
Brilliant Violet 421™ anti-human CD38 HIT2 FC
Brilliant Violet 711™ anti-human CD38 HIT2 FC
Brilliant Violet 785™ anti-human CD38 HIT2 FC
Brilliant Violet 605™ anti-human CD38 HIT2 FC
APC/Cyanine7 anti-human CD38 HIT2 FC
Purified anti-human CD38 (Maxpar® Ready) HIT2 FC,CyTOF®
PE/Dazzle™ 594 anti-human CD38 HIT2 FC
PE anti-human CD38 HIT2 FC
Brilliant Violet 510™ anti-human CD38 HIT2 FC
FITC anti-human CD38 HIT2 FC
PE/Dazzle™ 594 anti-human CD38 HIT2 FC
TotalSeq™-A0389 anti-human CD38 HIT2 PG
TotalSeq™-C0389 anti-human CD38 HIT2 PG
APC/Fire™ 750 anti-human CD38 HIT2 FC
TotalSeq™-B0389 anti-human CD38 HIT2 PG
APC/Fire™ 810 anti-human CD38 HIT2 FC
Spark NIR™ 685 anti-human CD38 Antibody HIT2 FC
TotalSeq™-D0389 anti-human CD38 HIT2 PG
PerCP/Cyanine5.5 anti-human CD38 HIT2 FC
APC anti-human CD38 HIT2 FC
APC/Fire™ 750 anti-human CD38 HIT2 FC
PE/Cyanine7 anti-human CD38 HIT2 FC
GMP PE anti-human CD38 HIT2 FC
GMP FITC anti-human CD38 HIT2 FC
Pacific Blue™ anti-human CD38 HIT2 FC
Pacific Blue™ anti-human CD38 HIT2 FC
GMP APC/Fire™ 750 anti-human CD38 HIT2 FC
GMP PE/Dazzle™ 594 anti-human CD38 HIT2 FC
GMP APC anti-human CD38 HIT2 FC
GMP PE/Cyanine7 anti-human CD38 HIT2 FC
Spark Blue™ 515 anti-human CD38 HIT2 FC
GMP Pacific Blue™ anti-human CD38 HIT2 FC
Spark Violet™ 423 anti-human CD38 HIT2 FC
Brilliant Violet 650™ anti-human CD38 HIT2 FC
Spark PLUS B550™ anti-human CD38 HIT2 FC
Go To Top Version: 1    Revision Date: 09/19/2022

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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