- Clone
- KF29 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- γ-Glutamyl transferase 1 (GGT1), γ-Glutamyl transpeptidase 1 (GGTP), GGT, GTG
- Isotype
- Mouse IgG1, κ
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Human peripheral blood lymphocytes were stained with CD3 APC and purified CD224 (clone KF29) (left) or Mouse IgG1, κ isotype control (right), followed by anti-mouse IgG1 PE
| Cat # | Size | Price | Quantity Check Availability | ||
|---|---|---|---|---|---|
| 394302 | 100 µg | $265.00 | |||
CD224, also known as γ-Glutamyl transferase 1 (GGT1), is a type I gamma-glutamyltransferase, and a member of the threonine peptidase family. CD224 consistes of a 380 amino acid heavy chain and a 189 amino acid light chain, which are translated from a single mRNA. It protects cells from oxidative stress by participating in γ-glutamyl cycle. CD224 is expressed on subset of T cells, B cells, stem cell precursor, endothelial cells and epithelial cells. It expresses on kidney, duodenuma and small intestine.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2734484 (BioLegend Cat. No. 394302)
Antigen Details
- Structure
- Type I gamma-glutamyltransferase
- Distribution
-
Subset of T cells, B cells, stem cell precursor, endothelial cells and epithelial cells
- Function
- Protects cells from oxidative stress by participating in γ-glutamyl cycle
- Ligand/Receptor
- Glutathione, GSH, Leukotriene C4, GSNO
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Hematopoietic stem and progenitors, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Mizushima T, et al. 2016. BMC. Cancer. 16:411.
- Wang Q, et al. 2017. Oncotarget. 8(22): 36171–36184.
- Jiang Y, et al. 2016. Mol. Med. 13(5):3813-20.
- Karp DR, et al. 1999. Int. Immunol. 11(11):1791-800.
- Gene ID
- 2678 View all products for this Gene ID
- UniProt
- View information about CD224 on UniProt.org
Other Formats
View All CD224 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD224 | KF29 | FC |
| PE anti-human CD224 | KF29 | FC |
| APC anti-human CD224 | KF29 | FC |
| TotalSeq™-C1052 anti-human CD224 | KF29 | PG |
| TotalSeq™-B1052 anti-human CD224 Antibody | KF29 | PG |
| TotalSeq™-A1052 anti-human CD224 | KF29 | PG |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD224
Human peripheral blood lymphocytes were stained with CD3 APC... -
PE anti-human CD224
Human peripheral blood lymphocytes were stained with CD3 APC... -
APC anti-human CD224
Human peripheral blood lymphocytes were stained with CD3 PE ... -
TotalSeq™-C1052 anti-human CD224
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TotalSeq™-B1052 anti-human CD224 Antibody
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TotalSeq™-A1052 anti-human CD224