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PE/Cyanine7 anti-human CD160 Antibody

Pricing & Availability
Clone
BY55 (See other available formats)
Regulatory Status
RUO
Other Names
BY55, NK1, NK28
Isotype
Mouse IgM, κ
Ave. Rating
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Product Citations
publications
BY55_PECyanine7_BY55_Antibody_1_032924
Human peripheral blood lymphocytes were stained with CD8 APC and CD160 (clone BY55) PE/Cyanine7 (left) or mouse IgM, κ PE/Cyanine7 isotype control (right).
  • BY55_PECyanine7_BY55_Antibody_1_032924
    Human peripheral blood lymphocytes were stained with CD8 APC and CD160 (clone BY55) PE/Cyanine7 (left) or mouse IgM, κ PE/Cyanine7 isotype control (right).
Compare all formats See PE/Cyanine7 spectral data
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341211 25 tests $176
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341212 100 tests $382
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Description

CD160 is a 27 kD GPI-anchored glycoprotein also known as BY55, NK1, and NK28. A member the Ig superfamily, CD160 exists as a disulfide-bond multimer, expressed on the surface of a subpopulation of NK cells, γ/δ T cells, subset of CD8+ T cells, and intestinal intraepithelial lymphocytes (IEL). CD160 plays costimulatory roles through binding to classical and nonclassical MHC-I molecules.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Anumanthan A, et al. 1998. J. Immunol. 161:2780.
  2. Maiza H, et al. 1993. J. Exp. Med. 178:1121.
Product Citations
  1. Li X, et al. 2019. Front Oncol. 1.115277778. PubMed
  2. Maas RJ, et al. 2020. Oncoimmunology. 9:1843247. PubMed
  3. Kong Y, et al. 2016. Clin Cancer Res. 22: 3057 - 3066. PubMed
  4. Collins DR, et al. 2021. Immunity. 54:2372. PubMed
  5. Kong Y, et al. 2015. Blood Cancer J. 5: 330. PubMed
RRID
AB_2562875 (BioLegend Cat. No. 341211)
AB_2562875 (BioLegend Cat. No. 341212)

Antigen Details

Structure
27 kD GPI-anchored glycoprotein, Ig superfamily
Distribution

Subpopulation of NK cells, γ/δ T cells, subset of CD8+ T cells, and intestinal intraepithelial lymphocytes (IEL)

Function
Costimulation
Ligand/Receptor
Classical and nonclassical MHC-I molecules
Cell Type
NK cells, T cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication.
2. Merino J, et al. 2007. Clin. Exp. Immunol. 149:87.
3. Barakonyi A, et al. 2004. J. Immunol. 173:5349.

Gene ID
11126 View all products for this Gene ID
UniProt
View information about CD160 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 12/03/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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