- Clone
- W19396D (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD103, ITAGE, integrin alpha E
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
110905 | 25 µg | 90€ | ||||
110906 | 100 µg | 269€ |
CD103 is the alpha E integrin, which forms a heterodimer with integrin beta 7. The heterodimer complex binds to E-cadherin. It is expressed in on T cells, notably in subpopulations in the lamina propria, on regulatory T cells, or resident memory T cells, and a subset of dendritic cells in gut mucosa. CD103 is thought to be involved with homing to intestinal epithelial sites and has been associated with high levels of TGF-beta presence.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse integrin alphaE/beta7
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- Application Notes
-
Clone W19396D can partially block binding of clone 2E7 on target cells.
- RRID
-
AB_2927988 (BioLegend Cat. No. 110905)
AB_2927988 (BioLegend Cat. No. 110906)
Antigen Details
- Structure
- 125 - 150 kD transmembrane glycoprotein, integrin
- Distribution
-
Lamina propria T cells, regulatory T cells, resident memory T cells, subset of dendritic cells
- Function
- Adhesion, localization and activation of intestinal lymphocytes, lymphocyte homing
- Interaction
- Integrin β7
- Ligand/Receptor
- E-Cadherin
- Cell Type
- Dendritic cells, Lymphocytes, T cells, Tregs
- Biology Area
- Cell Adhesion, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Parker CM, et al. 1992. Proc Natl Acad Sci U S A. 89:1924-8.
- Kruschwitz M, et al. 1991. J Clin Pathol. 44:636-45.
- Schon MP, et al. 1999. J. Immunol. 162:6641-9.
- Shaw SK, et al. 1994. J Biol Chem. 269:6016-25.
- Gene ID
- 3682 View all products for this Gene ID
- UniProt
- View information about CD103 on UniProt.org
Related FAQs
Other Formats
View All CD103 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD103 | W19396D | FC |
APC anti-mouse CD103 | W19396D | FC |
PE anti-mouse CD103 | W19396D | FC |
FITC anti-mouse CD103 | W19396D | FC |
PE/Cyanine7 anti-mouse CD103 | W19396D | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse CD103
C57BL/6 mouse splenocytes were stained with purified anti-mo... -
APC anti-mouse CD103
C57BL/6 mouse splenocytes were stained with anti-mouse CD103... -
PE anti-mouse CD103
C57BL/6 mouse splenocytes were stained with anti-mouse CD103... -
FITC anti-mouse CD103
C57BL/6 mouse splenocytes were stained with anti-mouse CD103... -
PE/Cyanine7 anti-mouse CD103
C57BL/6 mouse splenocytes were stained with anti-mouse CD103...
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