- Clone
- SA302A10 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- BOB, Brother of Bonzo
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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373007 | 25 tests | 164€ | ||||
373008 | 100 tests | 331€ |
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions, that is present on the cell surface as an homotrimer. Its ligand, GPR15L, was recently identified. It acts as receptor for human immunodeficiency virus type 1 and 2. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+ T cells responsible of the pathogenesis in colitis. It is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human GPR15-transfected cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_2650858 (BioLegend Cat. No. 373007)
AB_2650858 (BioLegend Cat. No. 373008)
Antigen Details
- Structure
- G-protein coupled receptor with 7 transmembrane regions, present in the cell surface as homotrimer.
- Distribution
-
Effector and memory T cells.
- Cell Type
- T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Nguyen LP, et al. 2015. Nat. Immunol. 16:207.
2. Kiene M, et al. 2014. PLoS One 9:e88195.
3. Cartwright A, et al. 2014. Cytokine. 67:53.
4. Kim SV, et al. 2013. Science. 340:1456.
5. Okamoto Y, et al. 2013. J. Biol. Chem. 288:9189. - Gene ID
- 2838 View all products for this Gene ID
- UniProt
- View information about GPR15 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
-
It is lot-specific. On average it ranges between 2-4.
Other Formats
View All GPR15 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
PE anti-human GPR15 | SA302A10 | FC |
APC anti-human GPR15 | SA302A10 | FC |
Brilliant Violet 421™ anti-human GPR15 | SA302A10 | FC |
PE/Cyanine7 anti-human GPR15 | SA302A10 | FC |
APC/Fire™ 750 anti-human GPR15 | SA302A10 | FC |
PE/Dazzle™ 594 anti-human GPR15 | SA302A10 | FC |
PerCP/Cyanine5.5 anti-human GPR15 | SA302A10 | FC |
TotalSeq™-B1298 anti-human GPR15 | SA302A10 | PG |
TotalSeq™-C1298 anti-human GPR15 | SA302A10 | PG |
TotalSeq™-A1298 anti-human GPR15 | SA302A10 | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-human GPR15
Human peripheral blood lymphocytes were stained with CD4 APC... -
APC anti-human GPR15
Human peripheral blood lymphocytes were stained with CD4 FIT... -
Brilliant Violet 421™ anti-human GPR15
Human peripheral blood lymphocytes were stained with CD4 APC... -
PE/Cyanine7 anti-human GPR15
Human peripheral blood lymphocytes were stained with CD4 FIT... -
APC/Fire™ 750 anti-human GPR15
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Dazzle™ 594 anti-human GPR15
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Cyanine5.5 anti-human GPR15
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-B1298 anti-human GPR15
-
TotalSeq™-C1298 anti-human GPR15
-
TotalSeq™-A1298 anti-human GPR15
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