PE anti-mouse TCR Vα11.1, 11.2 Antibody

Pricing & Availability
Clone
RR8-1 (See other available formats)
Regulatory Status
RUO
Other Names
Vα11 T-cell receptor,T cell receptor alpha 11
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
RR8-1_PE_071310
C57BL/6 mouse lymph node stained with TCR Vα11 (RR8-1) PE and CD3 (145-2C11) APC
  • RR8-1_PE_071310
    C57BL/6 mouse lymph node stained with TCR Vα11 (RR8-1) PE and CD3 (145-2C11) APC
See PE spectral data
Cat # Size Price Quantity Check Availability Save
139903 25 µg 129 CHF
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139904 100 µg 232 CHF
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Description

Vα11 T cell receptor (TCR Vα11) is a variant of TCR α chain and, along with TCR β chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through the interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The RR8-1 antibody is specific for b and d haplotypes of TCR Vα11.1 and Vα11.2, but not for Vα11.3. It does not react with a and c haplotypes of TCR Vα11.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse T-cell clone B10
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Jameson SC, et al. 1991. J. Immunol. 147:3185. (FC)
RRID
AB_10640825 (BioLegend Cat. No. 139903)
AB_10640825 (BioLegend Cat. No. 139904)

Antigen Details

Structure
Member of the immunoglobulin superfamily, Vα11 is a variant of the TCR α chain which associates with the TCR β chain to form the TCR heterodimer.
Distribution

Subset of TCR αβ+ T cells.

Function
Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.
Ligand/Receptor
MHC-peptide complex
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Gene ID
21473 View all products for this Gene ID
UniProt
View information about TCR Valpha11.1 11.2 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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