- Clone
- SA231A2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![SA231A2_PEDZL594_KLRG1_Antibody_1_032816 SA231A2_PEDZL594_KLRG1_Antibody_1_032816](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/SA231A2_PEDZL594_KLRG1_Antibody_1_032816.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes were stained with CD56 APC and KLRG1 (clone SA231A2) PE/Dazzle™ 594 (top) or mouse IgG2a, κ PE/Dazzle™ 594 isotype control (bottom). -
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
367710 | 100 tests | 382 CHF |
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human KLRG1-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm. - Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2572155 (BioLegend Cat. No. 367710)
Antigen Details
- Structure
- Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
- Distribution
-
Subsets of NK, effector and memory T cells.
- Function
- Inhibits cell activation and proliferation, marker of T cell senescence.
- Interaction
- AKT
- Ligand/Receptor
- E-, N-, and R- cadherins
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
-
1. Shi L, et al. 2014. J. Immunol. 192:649.
- Gene ID
- 10219 View all products for this Gene ID
- UniProt
- View information about KLRG1 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All KLRG1 Reagents Request Custom ConjugationCustomers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 Br... -
Alexa Fluor® 647 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD16 Br... -
Brilliant Violet 421™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
PE/Dazzle™ 594 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
APC anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PE anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
FITC anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 AP... -
APC/Fire™ 750 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
PE/Cyanine7 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 FI... -
TotalSeq™-A0153 anti-human KLRG1 (MAFA)
-
APC/Cyanine7 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 FI... -
KIRAVIA Blue 520™ anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with CD56 PE... -
TotalSeq™-B0153 anti-human KLRG1 (MAFA) Antibody
-
Alexa Fluor® 700 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with CD56 PE... -
APC/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-D0153 anti-human KLRG1 (MAFA)
-
PE/Fire™ 810 anti-human KLRG1 (MAFA) Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
TotalSeq™-C0153 anti-human KLRG1 (MAFA)
-
Spark NIR™ 685 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 640 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
Brilliant Violet 711™ anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 780 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PerCP/Fire™ 806 anti-human KLRG1 (MAFA)
Human lysed whole blood cells were stained with anti-human C... -
PE/Fire™ 700 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu... -
PE/Fire™ 744 anti-human KLRG1 (MAFA)
Human peripheral blood lymphocytes were stained with anti-hu...
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