- Clone
- 4H9/CD7 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- gp40
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![4H9-CD7_PURE_CD7_Antibody_093019 4H9-CD7_PURE_CD7_Antibody_093019](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/4H9-CD7_PURE_CD7_Antibody_093019.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood lymphocytes stained with CD4 APC and purified CD7 (clone 4H9/CD7) (left), or mouse IgG2a, κ isotype control (right), followed by anti-mouse IgG2a PE.
Cat # | Size | Price | Quantity Check Availability | Save | ||
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395602 | 100 µg | 112 CHF |
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- T-ALL blast cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
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- RRID
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AB_2820047 (BioLegend Cat. No. 395602)
Antigen Details
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 40 kD
- Distribution
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T cells, NK cells, thymocytes, hematopoietic progenitors, myeloid leukemic cell subsets
- Function
- T cell activation
- Ligand/Receptor
- Cytoplasmic domain associates with P13-kinase
- Cell Type
- Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
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- Barclay N, et al. 1993. The Leucocyte Antigen FactsBook. Academic Press Inc. San Diego.
- Stillwell R and Bierer BE. 2001. Immunol Res. 24:31-52.
- Rabinowich H, et al. 1994. J Immunol. 152:517-26.
- Gene ID
- 924 View all products for this Gene ID
- UniProt
- View information about CD7 on UniProt.org
Related FAQs
Other Formats
View All CD7 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD7 | 4H9/CD7 | FC |
PE anti-human CD7 | 4H9/CD7 | FC |
APC anti-human CD7 Antibody | 4H9/CD7 | FC |
PerCP/Cyanine5.5 anti-human CD7 Antibody | 4H9/CD7 | FC |
PE/Cyanine7 anti-human CD7 | 4H9/CD7 | FC |
FITC anti-human CD7 | 4H9/CD7 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD7
Human peripheral blood lymphocytes stained with CD4 APC and ... -
PE anti-human CD7
Human peripheral blood lymphocytes stained with CD4 APC and ... -
APC anti-human CD7 Antibody
Human peripheral blood lymphocytes were stained with CD4 FIT... -
PerCP/Cyanine5.5 anti-human CD7 Antibody
Human peripheral blood lymphocytes were stained with CD4 FIT... -
PE/Cyanine7 anti-human CD7
Human peripheral blood lymphocytes were stained with anti-hu... -
FITC anti-human CD7
Human peripheral blood lymphocytes were stained with anti-hu...
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