- Clone
- Poly19054 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Keratin, type I cytoskeletal 10, CK-10, keratin-10, cytokeratin 10
- Isotype
- Rabbit Polyclonal
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
905403 | 25 µg | 125 CHF | ||||
905404 | 100 µg | 350 CHF |
Keratin 10 is a member of the type 1 (acidic) cytokeratin family. Keratins, in general, are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse
- Reported Reactivity
- Dog, Non-Human Primate
- Antibody Type
- Polyclonal
- Host Species
- Rabbit
- Immunogen
- This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 10 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
WB - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 5.0 μg/ml is suggested. For Western blotting, a concentration range of 1.0 - 10 μg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This product may contain other non-IgG subtypes. -
Application References
(PubMed link indicates BioLegend citation) -
- Adams JR, et al. 2011. Cancer Res. 71:2706.
- Lacroix M, et al. 2010. Proc. Natl. Acad. Sci. USA 107:21076-21081. (IHC) PubMed
- Hu Y, et al. 2001. Nature 410:710.
- Yuspa SH, et al. 1989. J. Cell Biol. 109:1207.
- Liang Y. 2011. Patholog. Res. Int. 2011:936794. (IHC) PubMed
- Roop DR, et al. 1984. J. Biol. Chem. 259:8037.
- Product Citations
-
- RRID
-
AB_2616955 (BioLegend Cat. No. 905403)
AB_2616955 (BioLegend Cat. No. 905404)
Antigen Details
- Structure
- Keratin 10 is a 59 kD protein.
- Distribution
-
Cytoskeleton, extracellular, and nucleus.
- Function
- Keratin 10 generally associates with keratin 1. Keratin 10 mutations are associated with epidermolytic hyperkeratosis.
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Intermediate Filaments
- Gene ID
- 3858 View all products for this Gene ID
- UniProt
- View information about Keratin 10 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All Keratin 10 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Keratin 10 | Poly19054 | IHC-P,WB |
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