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Purified anti-RANTES (CCL5) Antibody

Pricing & Availability
Clone
VL1 (See other available formats)
Regulatory Status
RUO
Other Names
CCL5, C-C motif chemokine 5, Small-inducible cytokine A5, T-cell-specific protein RANTES, SIS-delta, T cell-specific protein P228, TCP228, Eosinophil-chemotactic cytokine, EoCP
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
VL1_PURE_RANTES_CCL5_Antibody_WB_050416
Western blot analysis of 50 ng recombinant human CCL5 (RANTES, carrier-free) (lane 1) and recombinant mouse CCL5 (RANTES, carrier-free) (lane 2) using anti-RANTES (CCL5) (clone VL1) antibody followed by HRP goat anti-mouse IgG (minimal x-reactivity) secondary antibody.
  • VL1_PURE_RANTES_CCL5_Antibody_WB_050416
    Western blot analysis of 50 ng recombinant human CCL5 (RANTES, carrier-free) (lane 1) and recombinant mouse CCL5 (RANTES, carrier-free) (lane 2) using anti-RANTES (CCL5) (clone VL1) antibody followed by HRP goat anti-mouse IgG (minimal x-reactivity) secondary antibody.
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515502 100 µg 153 CHF
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Description

RANTES (CCL5) is a member of the CC chemokine family. Its mature form consists of 68 amino acid residues. RANTES is a strong chemotractant for monocytes, NK cells, T cells, and eosinphils. RANTES may have important role in mediating immune and inflammatory responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IHC , ELISA - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 to 1.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Krensky AM, et al. 1997. Methods Enzymol. 287:162.
RRID
AB_2071299 (BioLegend Cat. No. 515502)

Antigen Details

Structure
Human RANTES cDNA is a member of the C-C chemokine family with a MW of around 8 kD. Human and mouse RANTES have 85% homology.
Distribution

Reported to be produced by T cells, platelets, synovial fibroblasts, and some tumor cells.

Function
Able to chemoattract monocytes, NK cells, eosinophils, and T cells.
Interaction
Monocytes, NK cells, T cells, and eosinophils.
Cell Type
Fibroblasts, Platelets, T cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
Cytokines/Chemokines
Antigen References

1. Von Luettichau. et al. 1996. Cytokine 8:89.
2. Schall TJ. 1991. Cytokine 3:165.

Gene ID
20304 View all products for this Gene ID
UniProt
View information about RANTES on UniProt.org
Go To Top Version: 4    Revision Date: 09.02.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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