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PerCP/Cyanine5.5 anti-mouse/human CD11b Antibody

Pricing & Availability
Clone
M1/70 (See other available formats)
Regulatory Status
RUO
Other Names
αM integrin, Mac-1, Mo1, CR3, Ly-40, C3biR, ITGAM
Isotype
Rat IgG2b, κ
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Product Citations
publications
M1slash70_PerCPCyanine55_CD11b_Antibody_111918
C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
  • M1slash70_PerCPCyanine55_CD11b_Antibody_111918
    C57BL/6 splenocytes were blocked with TruStain FcX™ (anti-mouse CD16/32) Antibody then stained with Ly-6G/Ly-6C (Gr-1) APC and CD11b (clone M1/70) PerCP/Cyanine5.5 (left) or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (right).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
101227 25 µg 72€
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101228 100 µg 234€
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Description

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human, Cynomolgus, Rhesus
Reported Reactivity
Chimpanzee, Baboon, Rabbit
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
C57BL/10 splenocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD11b antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone M1/70 has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F).

Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1,4, in vitro blocking3,9,12, depletion2,8, immunofluorescence microscopy6,7,10, immunohistochemistry of acetone-fixed frozen sections5,11-13, and spatial biology (IBEX)35,36. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 101248).

Application References

(PubMed link indicates BioLegend citation)
  1. Springer T, et al. 1978. Eur. J. Immunol. 8:539. (IP)
  2. Ault K and Springer T. 1981. J. Immunol. 126:359. (Deplete)
  3. Springer TA, et al. 1982. Immunol. Rev. 68:171. (Block)
  4. Ho MK and Springer TA. 1983. J. Biol. Chem. 258:2766. (IP)
  5. Flotte TJ, et al. 1983. Am. J. Pathol. 111:112. (IHC)
  6. Noel GJ, et al. 1990. J. Clin. Invest. 85:208. (IF)
  7. Allen LA and Aderem A. 1996. J. Exp. Med. 184:627 (IF)
  8. D'Amico A and Wu L. 2003. J. Exp. Med. 198:293. (Deplete)
  9. Brickson SJ, et al. 2003. Appl Physiol. 95:969. (Block)
  10. Clatworthy MR and Smith KG. 2004. J. Exp. Med. 199:717. (IF)
  11. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  12. Zhang Y, et al. 2002. J. Immunol. 168:3088. (IHC)
  13. Iwasaki A and Kelsall BL. 2001. J. Immunol. 166:4884 (IHC, FC)
  14. Tailleux L. 2003. J. Exp. Med. 197:121. (Block, FC)
  15. Olver S, et al. 2006. Cancer Research 66:571. (FC)
  16. Tan SL, et al. 2006. J. Immunol. 176:2872. (FC) PubMed
  17. Ponomarev ED, et al. 2006. J. Immunol. 176:1402. (FC)
  18. Dzhagalov I, et al. 2007. Blood 109:1620. (FC)
  19. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  20. Rasmussen JW, et al. 2006. Infect. Immun.74:6590. PubMed
  21. Napimoga MH, et al. 2008. J. Immunol. 180:609. PubMed
  22. Elqaraz-Carmon V, et al. 2008. J. Lipid. Res. 49:1894. PubMed
  23. Kim DD, et al. 2008. Blood 112:1109. PubMed
  24. Guo Y, et al. 2008. Blood 112:480. PubMed
  25. Norian LA, et al. 2009. Cancer Res. 69:3086. (FC) PubMed
  26. Baumgartner CK, et al. 2010. J. Immunol. 184:573. PubMed
  27. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  28. Whiteland J, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
  29. Weber GF, et al. 2014. J Exp Med. 211:1243. PubMed
  30. Ashok A, et al. 2015. Toxicol Sci. 143:64. PubMed
  31. Price PJ, et al. 2015. J Immunol. 194:1164. PubMed
  32. Doni A, et al. 2015. J Exp Med. 212:905. PubMed
  33. Ferreira R, et al. 2016. J Infect Dis. 213: 669 - 673. PubMed
  34. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  35. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  36. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Milasan A, et al. 2017. J Am Heart Assoc. 10.1161/JAHA.117.006892. PubMed
  2. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  3. Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
  4. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  5. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  6. Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed
  7. Grandjean CL, et al. 2021. Sci Adv. 7:. PubMed
  8. Leslie J, et al. 2021. Sci Rep. 11:1415. PubMed
  9. Zheng J, et al. 2022. Front Pharmacol. 13:866228. PubMed
  10. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  11. Tian WJ, et al. 2021. Clin Exp Pharmacol Physiol. 48:902. PubMed
  12. Ferrao Blanco MN, et al. 2022. Br J Pharmacol. 179:2771. PubMed
  13. Osokine I, et al. 2022. Cell Rep. 38:110329. PubMed
  14. Agarwalla P, et al. 2022. Nat Biotechnol. 40:1250. PubMed
  15. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  16. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  17. Marquardt RM, et al. 2022. Int J Mol Sci. 23: . PubMed
  18. Halin C, et al. 2022. EMBO J. 41:e111528. PubMed
  19. Auguste YSS, et al. 2022. Nat Neurosci. 25:1273. PubMed
  20. Schepers M, et al. 2023. Brain Behav Immun. 109:1. PubMed
  21. García-García A, et al. 2023. Bioact Mater. 24:174. PubMed
  22. Glaubitz J, et al. 2023. Gut. :. PubMed
  23. Zhang K, et al. 2023. Nat Metab. 5:129. PubMed
  24. Arimoto KI, et al. 2023. Nat Commun. 14:251. PubMed
  25. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  26. Lazure F, et al. 2023. Nat Commun. 14:535. PubMed
  27. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  28. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  29. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  30. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  31. Wilden A, et al. 2022. Front Immunol. 13:991295. PubMed
  32. Lee T, et al. 2014. Mol Biol Cell. 25:583. PubMed
  33. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  34. Orberg E, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.53. PubMed
  35. Liu Y, et al. 2021. Cell Metabolism. 33(6):1221-1233.e11. PubMed
  36. Peng W, et al. 2022. Cell Mol Life Sci. 79:602. PubMed
  37. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  38. Zhu S, et al. 2023. J Nanobiotechnology. 21:81. PubMed
  39. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  40. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  41. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  42. Shen Z, et al. 2023. iScience. 26:106572. PubMed
  43. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  44. John S, et al. 2020. Sci Rep. 10:11377. PubMed
  45. Hastings AK, et al. 2019. iScience. 13:339. PubMed
  46. Kim SS, et al. 2022. Cancers (Basel). 14:. PubMed
  47. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  48. Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
  49. Hong M, et al. 2021. Int J Mol Sci. 22:. PubMed
  50. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  51. Zhao X, et al. 2022. Front Mol Biosci. 9:786864. PubMed
  52. Meng W, et al. 2021. JCI Insight. 6:. PubMed
  53. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  54. McNamara HA, et al. 2020. Cell Host Microbe. 572:28. PubMed
  55. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  56. Gern BH, et al. 2021. Cell Host Microbe. 29(4):594-606.e6. PubMed
  57. Kaczanowska S, et al. 2021. Cell. 184(8):2033-2052.e21. PubMed
  58. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  59. Fu B et al. 2017. Immunity. 47(6):1100-1113 . PubMed
  60. Chen L, et al. 2019. Cell Mol Gastroenterol Hepatol. 7:623. PubMed
  61. Kenichi Shimada et al. 2018. Immunity. 49(5):873-885 . PubMed
  62. Kobayashi T, et al. 2019. Cell. 176:982. PubMed
  63. Shen Y, et al. 2021. Comput Struct Biotechnol J. 19:5360. PubMed
  64. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  65. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  66. Zasłona Z, et al. 2014. J Immunol. 193:4245. PubMed
  67. Leach SM, et al. 2020. Cell Rep. 33:108337. PubMed
  68. Dong L, et al. 2021. Cancer Cell. . PubMed
  69. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  70. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  71. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  72. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  73. Biswas S, et al. 2021. Nature. 591:464. PubMed
  74. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  75. Yuan Q, et al. 2021. Cell Reports. 34(5):108724. PubMed
  76. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  77. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  78. Sun P, et al. 2015. J Hepatol. . PubMed
  79. Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed
  80. Cai B, et al. 2021. Mol Cancer. 20:165. PubMed
  81. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  82. Xiong A, et al. 2022. EBioMedicine. 83:104239. PubMed
  83. Galle E, et al. 2022. Genome Biol. 23:207. PubMed
  84. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  85. Neubert K, et al. 2014. J Immunol. 192:5830. PubMed
  86. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  87. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  88. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  89. Koh EH, et al. 2018. Diabetes. 67(12). PubMed
  90. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  91. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  92. Jiao H, et al. 2021. Cell. 184(11):2896-2910.e13. PubMed
  93. Lu S, et al. 2020. JCI Insight. 5:00. PubMed
  94. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  95. Plein A, et al. 2018. Nature. 562:223. PubMed
  96. Jeong SJ, et al. 2021. Autophagy. 17:3740. PubMed
  97. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  98. Fulham MA, et al. 2019. Am J Physiol Cell Physiol. 317:C687. PubMed
  99. Gu H, et al. 2018. Aging (Albany NY). 1.525694444. PubMed
  100. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  101. Xu G, et al. 2022. Cell Death Dis. 13:888. PubMed
  102. Raineri D, et al. 2021. Biomedicines. 10:. PubMed
  103. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  104. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  105. Bunn P, et al. 2014. J Immunol. 192:3709. PubMed
  106. Nishi C, et al. 2014. Mol Cell Biol. 34:1512. PubMed
  107. Yue X, et al. 2019. Nat Commun. 10:2011. PubMed
  108. Pereira JA, et al. 2020. Hum Mol Genet. 29:1253. PubMed
  109. Lu CY, et al. 2020. J Neurosci. 40:9602. PubMed
  110. Okamura T, et al. 2021. Front Immunol. 12:669629. PubMed
  111. Qian SJ, et al. 2021. Front Immunol. 12:711337. PubMed
  112. Wang J, et al. 2021. Nat Commun. 12:6198. PubMed
  113. Fennell LM, et al. 2020. EMBO J. 39:e103303. PubMed
  114. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  115. Li W, et al. 2021. Front Pharmacol. 12:697483. PubMed
  116. Yu Y, et al. 2022. Nat Commun. 13:6857. PubMed
  117. Bretscher P, et al. 2015. EMBO Mol Med. 7:593. PubMed
  118. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  119. Qi T, et al. 2020. Cell Rep. 33:108452. PubMed
  120. Bogie JF, et al. 2020. Ther Adv Chronic Dis. 11:2040622320947378. PubMed
  121. Nayak RR, et al. 2021. Cell Host Microbe. 29(3):362-377.e11. PubMed
  122. Zhang F, et al. 2020. EMBO Mol Med. e12034:12. PubMed
  123. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  124. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  125. Wei W, et al. 2022. mSystems. 7:e0046922. PubMed
  126. , et al. 2021. Eur J Immunol. 51:2708. PubMed
  127. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  128. Xu M, et al. 2022. Genes Dis. 9:429. PubMed
  129. Xu Z, et al. 2020. Cancer Immunol Res. 1354:8. PubMed
  130. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  131. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  132. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  133. Lu S, et al. 2020. Arterioscler Thromb Vasc Biol. 40:394. PubMed
  134. Sun L, et al. 2015. J Immunol. 194:4891. PubMed
  135. Chung L et al. 2018. Cell host & microbe. 23(2):203-214 . PubMed
  136. Sasaki T, et al. 2020. Cell Reports. 28(1):202-217.e7.. PubMed
  137. Deczkowska A, et al. 2017. Nat Commun. 8:717. PubMed
  138. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  139. Carbone C, et al. 2021. J Immunother Cancer. 9:. PubMed
  140. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  141. Anger-Góra N, et al. 2021. Oncol Lett. 22:582. PubMed
  142. Sharma A, et al. 2020. Cell. 183(2):377-394.e21. PubMed
  143. Liu Z, et al. 2021. Immunity. 54(2):247-258.e7. PubMed
  144. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  145. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  146. Lin W, et al. 2019. EBioMedicine. 49:133. PubMed
  147. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  148. Brown SM et al. 2017. Endocrinology. 158(10):3592-3604 . PubMed
  149. López MJ, et al. 2018. Invest Ophthalmol Vis Sci. 59:5671. PubMed
  150. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  151. Wu S, et al. 2022. BMC Immunol. 23:17. PubMed
  152. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  153. Zhao D, et al. 2020. Cancer Discov. 10:1374. PubMed
  154. Cruz-Herranz A, et al. 2021. JCI Insight. 6: . PubMed
  155. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  156. Stowe CL, et al. 2019. eLife. 0.333333333333333. PubMed
  157. Chatterjee D, et al. 2021. Cell Reports. 35(2):108996. PubMed
  158. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  159. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  160. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  161. Bhattacharya A, et al. 2018. Neuropsychopharmacology. 43:2586. PubMed
  162. Carestia A, et al. 2019. Cell Rep. 28:896. PubMed
  163. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  164. Chruewkamlow N, et al. 2021. Stem Cell Res Ther. 12:520. PubMed
  165. Vachon L, et al. 2022. Theranostics. 12:1440. PubMed
  166. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  167. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  168. Ni C, et al. 2021. Infect Immun. 89:. PubMed
  169. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  170. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  171. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  172. Dulken BW, et al. 2019. Nature. 571:205. PubMed
  173. Muri J, et al. 2020. eLife. 9:e53627.. PubMed
  174. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  175. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  176. Hightower RM, et al. 2019. Mol Ther. 28:189. PubMed
  177. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  178. Bitschar K, et al. 2019. Nat Commun. 10:2730. PubMed
  179. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  180. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  181. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  182. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  183. Raoof R, et al. 2021. J Neurosci. 41:8249. PubMed
  184. Guo D, et al. 2022. Bone Res. 10:45. PubMed
  185. Tozuka M, et al. 2016. J Dermatol Sci. 82: 38-45. PubMed
  186. Sharif O, et al. 2013. J Immunol. 190:5640. PubMed
  187. Bennett FC, et al. 2018. Neuron. 98:1170. PubMed
  188. Yang X, et al. 2018. Sci Rep. 8:188. PubMed
  189. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  190. Nagashima H et al. 2019. Immunity. 51(4):682-695 . PubMed
  191. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  192. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  193. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  194. Unsinger J, et al. 2021. J Leukoc Biol. 109:697. PubMed
  195. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  196. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  197. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  198. Muchenditsi A, et al. 2017. Am J Physiol Gastrointest Liver Physiol. 313:G39. PubMed
  199. Tothova Z et al. 2017. Cell stem cell. 21(4):547-555 . PubMed
  200. Zhu K, et al. 2022. EMBO Rep. 23:e54499. PubMed
  201. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  202. Xu JL, et al. 2022. Front Pharmacol. 13:911663. PubMed
  203. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  204. Hakim R, et al. 2021. J Neurosci. 41:8441. PubMed
  205. Gu H, et al. 2021. Elife. 10:. PubMed
  206. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  207. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  208. Dallari S, et al. 2021. Cell Host Microbe. 29(6):1014-1029.e8. PubMed
  209. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  210. Rustenhoven J, et al. 2021. Cell. 184(4):1000-1016.e27. PubMed
  211. Liao Y, et al. 2020. Theranostics. 7.113888889. PubMed
  212. Starr T, et al. 2018. PLoS One. 13:e0193601. PubMed
  213. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  214. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  215. Meng Michelle Xu et al. 2017. Immunity. 47(2):363-373 . PubMed
  216. Jaitin DA et al. 2016. Cell. 167(7):1883-1896 . PubMed
  217. Zhang J, et al. 2018. Oncoimmunology. 7:e1461301. PubMed
  218. Werner A, et al. 2021. iScience. 24:103076. PubMed
  219. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  220. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  221. Chen J, et al. 2017. Sci Rep. 10.1038/s41598-017-00654-2. PubMed
  222. Danzer H, et al. 2020. Elife. 9:00. PubMed
  223. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  224. Stefan KL, et al. 2020. Cell. 1312:183. PubMed
  225. Molgora M, et al. 2020. Cell. 182:886. PubMed
  226. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  227. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  228. Bohlen CJ et al. 2017. Neuron. 94(4):759-773 . PubMed
  229. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  230. Ishihara J, et al. 2018. Nat Commun. 9:2163. PubMed
  231. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  232. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  233. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  234. Sakamoto K, et al. 2022. STAR Protoc. 3:101052. PubMed
  235. Tummala G, et al. 2021. Invest Ophthalmol Vis Sci. 62:41. PubMed
  236. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  237. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  238. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  239. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  240. Guey B, et al. 2014. Proc Natl Acad Sci U S A. 111:17254. PubMed
  241. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  242. Koyama M et al. 2019. Immunity. 51(5):885-898 . PubMed
  243. Zheng C, et al. 2021. J Extracell Vesicles. 10:e12109. PubMed
  244. Tripathi A, et al. 2021. Mol Psychiatry. 26:3043. PubMed
  245. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  246. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  247. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  248. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  249. Lee J, et al. 2015. Nat Commun. 6: 8499. PubMed
  250. Sen D, et al. 2016. PLoS One. 11:e0165064. PubMed
  251. Liddelow S, et al. 2017. Nature. 541:481-487. PubMed
  252. Xu Z, et al. 2020. Cell Rep. 32:108041. PubMed
  253. Ang QY, et al. 2020. Cell. 181(6):1263-1275.e16. PubMed
  254. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  255. Strattan E, et al. 2020. Frontiers in Immunology. 2.131944444. PubMed
  256. Ribechini E, et al. 2017. Blood Adv. 0.699305556. PubMed
  257. Tan DQ, et al. 2019. Cell Rep. 26:2316. PubMed
  258. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  259. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
  260. Chithanathan K, et al. 2022. Biology (Basel). 11:. PubMed
  261. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  262. Erens C, et al. 2022. Biomedicines. 10:. PubMed
  263. Yang F, et al. 2021. Nat Commun. 12:3424. PubMed
  264. Kapralov AA, et al. 2020. Nat Chem Biol. 278:16. PubMed
  265. Zheng H, et al. 2021. Frontiers in Immunology. 12:645100. PubMed
  266. Han J, et al. 2015. Cancer Res . 75: 5273 - 5282. PubMed
RRID
AB_893232 (BioLegend Cat. No. 101227)
AB_893232 (BioLegend Cat. No. 101228)

Antigen Details

Structure
Integrin family, associates with integrin β2 (CD18), 170 kD
Distribution

Granulocytes, monocytes/macrophages, dendritic cells, NK cells, subsets of T and B cells

Function
Adhesion, chemotaxis
Ligand/Receptor
ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, fibrinogen
Cell Type
B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Coxon A, et al. 1996. Immunity 5:653.

Gene ID
16409 View all products for this Gene ID 3684 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD11b
Specificity Alt (DOES NOT SHOW ON TDS):
CD11b
App Abbreviation (DOES NOT SHOW ON TDS):
FC
UniProt
View information about CD11b on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD11b Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse/human CD11b M1/70 FC
Biotin anti-mouse/human CD11b M1/70 FC
FITC anti-mouse/human CD11b M1/70 FC
PE anti-mouse/human CD11b M1/70 FC,IHC
PE/Cyanine5 anti-mouse/human CD11b M1/70 FC
Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,IHC-F,ICC
PE/Cyanine7 anti-mouse/human CD11b M1/70 FC
Alexa Fluor® 488 anti-mouse/human CD11b M1/70 FC,IHC-F,3D IHC,SB
Alexa Fluor® 647 anti-mouse/human CD11b M1/70 FC,3D IHC,SB
Alexa Fluor® 700 anti-mouse/human CD11b M1/70 FC
Pacific Blue™ anti-mouse/human CD11b M1/70 FC
APC/Cyanine7 anti-mouse/human CD11b M1/70 FC
PerCP/Cyanine5.5 anti-mouse/human CD11b M1/70 FC
PerCP anti-mouse/human CD11b M1/70 FC
Brilliant Violet 421™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 570™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 605™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 650™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 711™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 785™ anti-mouse/human CD11b M1/70 FC
Brilliant Violet 510™ anti-mouse/human CD11b M1/70 FC,ICC
Ultra-LEAF™ Purified anti-mouse/human CD11b M1/70 FC,CyTOF®,IP,Block,Depletion,IHC-F,ICC
Purified anti-mouse/human CD11b (Maxpar® Ready) M1/70 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD11b M1/70 IHC-F,FC
PE/Dazzle™ 594 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 750 anti-mouse/human CD11b M1/70 FC
TotalSeq™-A0014 anti-mouse/human CD11b M1/70 PG
Brilliant Violet 750™ anti-mouse/human CD11b M1/70 FC
TotalSeq™-B0014 anti-mouse/human CD11b M1/70 PG
TotalSeq™-C0014 anti-mouse/human CD11b M1/70 PG
Spark NIR™ 685 anti-mouse/human CD11b M1/70 FC
PE/Fire™ 640 anti-mouse/human CD11b M1/70 FC
Spark YG™ 593 anti-mouse/human CD11b M1/70 FC
Spark YG™ 570 anti-mouse/human CD11b M1/70 IHC-F
PE/Fire™ 810 anti-mouse/human CD11b M1/70 FC
APC/Fire™ 810 anti-mouse/human CD11b Antibody M1/70 FC
Spark Blue™ 550 anti-mouse/human CD11b M1/70 FC
Spark UV™ 387 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 806 anti-mouse/human CD11b M1/70 FC
PerCP/Fire™ 780 anti-mouse/human CD11b M1/70 FC
Spark Blue™ 574 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
KIRAVIA Blue 520™ anti-mouse/human CD11b M1/70 FC
PE/Fire™ 744 anti-mouse/human CD11b M1/70 FC
Spark PLUS UV395™ anti-mouse/human CD11b M1/70 FC
Spark Red™ 718 anti-mouse/human CD11b (Flexi-Fluor™) M1/70 FC
Go To Top Version: 2    Revision Date: 11/19/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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