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- Clone
- 201A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CLEC4C, CLECSF11, CLECSF7, DLEC, HECL
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes and monocytes were stained with True-Stain Monocyte Blocker™ (Cat. No. 426103), CD123 FITC, and CD303 (BDCA-2, clone 201A) APC/Fire™ 750 (left) or mouse IgG2a, κ APC/Fire™ 750 isotype control (right).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 354235 | 25 tests | 123€ | ||||
| 354236 | 100 tests | 306€ | ||||
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Fire™ 750 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm. - Excitation Laser
-
Red Laser (633 nm)
-
Application References
(PubMed link indicates BioLegend citation) - RRID
-
AB_2783259 (BioLegend Cat. No. 354235)
AB_2783259 (BioLegend Cat. No. 354236)
Antigen Details
- Structure
- Type II transmembrane protein, 38 kD, member of the C-type lectin superfamily
- Distribution
-
Plasmacytoid dendritic cells
- Function
- Antigen capture, inhibition of IFN α/β production
- Cell Type
- Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Jähn PS, et al. 2010. Cell Immunol. 265:15.
2. Graham LM and Brown GD. 2009. Cytokine 48:148.
3. Röck J, et al. 2007. Eur. J. Immunol. 37:3564.
4. Dzionek A, et al. 2001. J. Exp. Med. 194:1823. - Gene ID
- 170482 View all products for this Gene ID
- UniProt
- View information about CD303 on UniProt.org
Related Pages & Pathways
Pathways
Other Formats
View All CD303 Reagents Request Custom ConjugationCustomers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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APC anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 P... 
-
Purified anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with purifie... 
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PE anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
-
FITC anti-human CD303 (BDCA-2)
Human peripheral blood mononuclear cells were stained with C... 
-
PerCP/Cyanine5.5 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with anti-hu... -
Brilliant Violet 421™ anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
-
PE/Cyanine7 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... -
Purified anti-human CD303 (BDCA-2) (Maxpar® Ready)
Human PBMCs stained with 151Eu-anti-CD123 (6H6) and 153Eu-an... -
Alexa Fluor® 647 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 P... 
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Biotin anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
-
Brilliant Violet 785™ anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
-
Brilliant Violet 605™ anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
-
PE/Dazzle™ 594 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 A... 
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Alexa Fluor® 700 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with CD123 P... 
-
Alexa Fluor® 488 anti-human CD303 (BDCA-2)
RBC lysed human blood was stained with CD123 APC and CD303 (... 
-
Brilliant Violet 510™ anti-human CD303 (BDCA-2)
Human peripheral blood lymphocytes were stained with CD123 A... -
Brilliant Violet 711™ anti-human CD303 (BDCA-2)
Human peripheral blood lymphocytes were stained with CD123 P... -
APC/Fire™ 750 anti-human CD303 (BDCA-2)
Human peripheral blood lymphocytes and monocytes were stain... -
APC/Cyanine7 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with with Tr... -
TotalSeq™-A0370 anti-human CD303 (BDCA-2)
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TotalSeq™-C0370 anti-human CD303 (BDCA-2)
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TotalSeq™-B0370 anti-human CD303 (BDCA-2)
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TotalSeq™-D0370 anti-human CD303 (BDCA-2)
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Spark Blue™ 550 anti-human CD303 (BDCA-2) (Flexi-Fluor™)
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Spark Red™ 718 anti-human CD303 (BDCA-2) (Flexi-Fluor™)
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APC/Fire™ 810 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with anti-hu... -
Spark Violet™ 538 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with anti-hu... -
PerCP/Fire™ 806 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were stained with anti-hu...
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