- Clone
- QA17A09 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- c-KIT, Stem Cell Factor Receptor, SCFR
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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155102 | 500 µg | 203€ |
CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- Murine IL-3 dependent mast cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2734232 (BioLegend Cat. No. 155102)
Antigen Details
- Structure
- Growth factor receptor, tyrosine kinase
- Distribution
-
Hematopoietic stem cells, AML, mast cells, oocytes, interstitial theca cells, leydig cells
- Function
- Growth factor receptor, tyrosine kinase
- Ligand/Receptor
- Stem Cell Factor (SCF)
- Cell Type
- Hematopoietic stem and progenitors, Leukemia, Mast cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Barclay AN, Brown MH. 1997. Biochem. Soc. Trans. 25:224-8.
- Galli SJ, et al. 1994. Adv. Immunol. 55:1.
- Ikuta K, et al. 1992. Annu. Rev. Immunol. 10:759.
- Besmer P, et al. 1986. Nature. 320:415-21.
- Witte ON. 1990. Cell. 63:5.
- Gene ID
- 16590 View all products for this Gene ID
- UniProt
- View information about CD117 on UniProt.org
Other Formats
View All CD117 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD117 (c-kit) Recombinant Antibody | QA17A09 | FC |
PE anti-mouse CD117 (c-kit) Recombinant Antibody | QA17A09 | FC |
APC anti-mouse CD117 (c-kit) Recombinant Antibody | QA17A09 | FC |
FITC anti-mouse CD117 (c-kit) Recombinant Antibody | QA17A09 | FC |
Brilliant Violet 421™ anti-mouse CD117 (c-kit) Recombinant Antibody | QA17A09 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD117 (c-kit) Recombinant Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
PE anti-mouse CD117 (c-kit) Recombinant Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
APC anti-mouse CD117 (c-kit) Recombinant Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b PE a... -
FITC anti-mouse CD117 (c-kit) Recombinant Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
Brilliant Violet 421™ anti-mouse CD117 (c-kit) Recombinant Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b FITC...
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