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FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg 29€
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103108 500 µg 84€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  2. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  3. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  4. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  5. Sefik E, et al. 2022. Nature. 606:585. PubMed
  6. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  7. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  8. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  9. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  10. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  11. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  12. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  13. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  14. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  15. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  16. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  17. Zheng Z, et al. 2022. Cells. 11: . PubMed
  18. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  19. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  20. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  21. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  22. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  23. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  24. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  25. Liu X, et al. 2022. Pain. 163:508. PubMed
  26. González H, et al. 2022. Cell. 185:729. PubMed
  27. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  28. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  29. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  30. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  31. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  32. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  33. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  34. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  35. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  36. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  37. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  38. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  39. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  40. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  41. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  42. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  43. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  44. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  45. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  46. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  47. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  48. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  49. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  50. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  51. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  52. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  53. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  54. Li L, et al. 2023. iScience. 26:106095. PubMed
  55. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  56. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  57. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  58. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  59. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  60. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  61. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  62. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  63. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  64. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  65. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  66. Wang X, et al. 2023. Nature. 618:808. PubMed
  67. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  68. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  69. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  70. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  71. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  72. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  73. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  74. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  75. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  76. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  77. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  78. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  79. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  80. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  81. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  82. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  83. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  84. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  85. Zhu H, et al. 2018. Elife. 7:. PubMed
  86. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  87. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  88. Saito S, et al. 2020. Nutrients. 12:. PubMed
  89. Liu X, et al. 2020. Nature. . PubMed
  90. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  91. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  92. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  93. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  94. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  95. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  96. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  97. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  98. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  99. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  100. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  101. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  102. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  103. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  104. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  105. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  106. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  107. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  108. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  109. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  110. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  111. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  112. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  113. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  114. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  115. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  116. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  117. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  118. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  119. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  120. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  121. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  122. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  123. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  124. Zhang X, et al. 2022. Cells. 11:. PubMed
  125. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  126. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  127. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  128. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  129. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  130. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  131. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  132. Plein A, et al. 2018. Nature. 562:223. PubMed
  133. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  134. Green DP, et al. 2019. Neuron. 101:412. PubMed
  135. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  136. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  137. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  138. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  139. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  140. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  141. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  142. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  143. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  144. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  145. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  146. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  147. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  148. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  149. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  150. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  151. Li J, et al. 2020. Elife. 9:00. PubMed
  152. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  153. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  154. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  155. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  156. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  157. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  158. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  159. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  160. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  161. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  162. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  163. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  164. Wan X, et al. 2018. Nature. 560:107. PubMed
  165. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  166. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  167. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  168. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  169. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  170. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  171. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  172. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  173. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  174. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  175. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  176. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  177. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  178. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  179. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  180. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  181. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  182. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  183. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  184. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  185. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  186. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  187. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  188. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  189. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  190. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  191. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  192. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  193. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  194. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  195. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  196. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  197. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  198. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  199. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  200. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  201. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  202. Long JT, et al. 2022. Elife. 11:. PubMed
  203. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  204. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  205. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  206. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  207. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  208. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  209. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  210. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  211. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  212. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  213. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  214. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  215. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  216. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  217. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  218. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  219. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  220. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  221. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  222. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  223. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  224. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  225. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  226. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  227. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  228. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  229. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  230. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  231. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  232. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  233. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  234. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  235. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  236. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  237. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  238. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  239. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  240. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  241. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  242. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  243. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  244. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  245. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  246. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  247. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  248. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  249. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  250. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  251. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  252. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  253. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  254. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  255. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  256. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  257. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  258. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  259. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  260. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  261. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  262. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  263. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  264. Sheng J, et al. 2021. eLife. 10:00. PubMed
  265. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  266. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  267. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  268. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  269. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  270. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  271. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  272. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  273. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  274. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  275. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  276. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  277. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  278. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  279. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  280. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  281. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  282. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  283. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  284. Dingler FA, et al. 2020. Mol Cell. . PubMed
  285. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  286. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  287. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  288. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  289. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  290. Wolf Y, et al. 2019. Cell. 179:219. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312972 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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