- Clone
- J143 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Integrin alpha-3, FRP-2, galactoprotein B3, VLA-3 subunit alpha, CD49 antigen-like family member C, antigen identified by monoclonal antibody J143, very late activation protein 3 receptor, alpha-3 subunit
- Previously
-
Signet Catalog# 8010-01
Covance Catalog# SIG-38010
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
917201 | 1 mL | 322€ |
The alpha 3 subunit of VLA-3 consists of the ECMR I (extracellular matrix receptor I) and URO-1. VLA-3 is also known as CD49c and forms a heterodimer with β1 integrin for cell adhesion functions. In tissues, the URO-1 antigen is expressed by glomeruli, the basal layer of transitional epithelium and skin, and the basement membrane of glands. URO-1 may serve as a helpful marker of certain tumors, as it has been found to be expressed in bladder tumors, most kidney and certain other epithelial tumors.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was developed using the 253J Bladder cancer cell line.
- Formulation
-
Phosphate-buffered solution with BSA + 0.09% NaN3.
Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. For further information please contact BioLegend Technical Support or Customer Service. - Preparation
- The antibody was purified by affinity chromatography.
- Storage & Handling
- Store between 2°C and 8°C.
- Application
-
IHC-F - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue section. For immunohistochemistry, a dilution of 1:40 is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
-
- Hemler M, et al. 1988. J Biol Chem. 263:7660.
- Cordon-Cardo C, et al. 1984. J Histochem Cytochem. (10): 1035-40. (IHC-F)
- RRID
-
AB_2565195 (BioLegend Cat. No. 917201)
Related Pages & Pathways
Pages
Other Formats
View All URO-1 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-URO-1 | J143 | IHC-F |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-URO-1
IHC staining of purified anti-URO-1 antibody (clone J143) on...
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