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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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Cat # Size Price Save
101301 50 µg ¥7,920
101302 500 µg ¥25,300
Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  2. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  3. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  4. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  5. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  6. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  7. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  8. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  9. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  10. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  11. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  12. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  13. Ding P, et al. 2022. Elife. 11:. PubMed
  14. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  15. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  16. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  17. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  18. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  19. Li L, et al. 2023. iScience. 26:106095. PubMed
  20. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  21. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  22. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  23. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  24. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  25. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  26. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  27. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  28. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  29. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  30. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  31. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  32. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  33. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  34. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  35. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  36. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  37. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  38. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  39. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  40. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  41. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  42. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  43. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  44. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  45. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  46. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  47. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  48. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  49. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  50. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  51. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  52. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  53. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  54. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  55. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  56. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  57. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  58. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  59. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  60. Miyao T, et al. 2022. Elife. 11: . PubMed
  61. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  62. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  63. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  64. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  65. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  66. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  67. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  68. Akalu YT, et al. 2022. Elife. 11: . PubMed
  69. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  70. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  71. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  72. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  73. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  74. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  75. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  76. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  77. Cousin N, et al. 2022. Cells. 12: . PubMed
  78. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  79. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  80. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  81. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  82. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  83. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  84. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  85. Liu X, et al. 2022. Pain. 163:508. PubMed
  86. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  87. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  88. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  89. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  90. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  91. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  92. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  93. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  94. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  95. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  96. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  97. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  98. Barkaway A, et al. 2021. Immunity. . PubMed
  99. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  100. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  101. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  102. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  103. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  104. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  105. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  106. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  107. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  108. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  109. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  110. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  111. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  112. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  113. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  114. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  115. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  116. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  117. Mevel R, et al. 2020. eLife. 9:00. PubMed
  118. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  119. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  120. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  121. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  122. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  123. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  124. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  125. Goel S, et al. 2017. Nature. 548:471. PubMed
  126. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  127. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  128. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  129. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  130. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  131. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  132. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  133. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  134. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  135. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  136. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  137. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  138. Feng J, et al. 2021. iScience. 24:103004. PubMed
  139. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  140. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  141. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  142. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  143. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  144. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  145. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  146. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  147. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  148. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  149. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  150. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  151. Diao L, et al. 2022. iScience. 25:105511. PubMed
  152. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  153. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  154. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  155. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  156. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  157. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  158. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  159. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  160. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  161. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  162. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  163. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  164. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  165. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  166. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  167. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  168. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  169. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  170. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  171. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  172. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  173. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  174. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  175. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  176. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  177. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  178. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  179. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  180. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  181. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  182. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  183. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  184. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  185. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  186. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  187. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  188. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  189. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  190. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  191. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  192. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  193. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  194. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  195. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  196. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  197. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  198. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  199. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  200. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  201. Tal MC, et al. 2020. MBio. 11:00. PubMed
  202. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  203. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  204. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  205. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  206. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  207. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  208. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  209. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  210. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  211. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  212. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  213. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  214. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  215. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  216. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  217. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  218. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  219. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  220. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  221. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  222. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  223. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  224. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  225. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  226. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  227. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  228. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  229. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  230. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  231. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  232. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  233. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  234. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  235. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  236. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  237. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  238. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  239. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  240. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  241. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  242. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  243. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  244. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  245. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  246. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  247. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  248. Wong HS, et al. 2021. Cell. . PubMed
  249. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  250. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  251. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  252. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  253. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  254. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  255. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  256. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  257. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  258. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  259. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  260. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  261. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  262. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  263. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  264. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  265. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  266. Baasch S, et al. 2021. Cell. . PubMed
  267. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  268. Zheng J, et al. 2020. bioRxiv. . PubMed
  269. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  270. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  271. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  272. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  273. Roy K, et al. 2019. Immunity. 50:616. PubMed
  274. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  275. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  276. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  277. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  278. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  279. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  280. Welte T, et al. 2021. iScience. 24:103349. PubMed
  281. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  282. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  283. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  284. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  285. Xu S, et al. 2021. Immunity. . PubMed
  286. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  287. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  288. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  289. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  290. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  291. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  292. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  293. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  294. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  295. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  296. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  297. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  298. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  299. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  300. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  301. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  302. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  303. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  304. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  305. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  306. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  307. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  308. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  309. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  310. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  311. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  312. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  313. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  314. Zheng J, et al. 2020. Nature. . PubMed
  315. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  316. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  317. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  318. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  319. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  320. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  321. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  322. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  323. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  324. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  325. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  326. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  327. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  328. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  329. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  330. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  331. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  332. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  333. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  334. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  335. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  336. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  337. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  338. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  339. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  340. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  341. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  342. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  343. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  344. Lenert R 2005. J Immunol. 174:2429. PubMed
  345. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  346. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  347. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  348. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  349. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  350. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  351. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  352. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  353. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  354. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  355. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  356. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  357. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  358. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  359. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  360. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  361. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  362. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  363. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  364. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  365. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  366. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  367. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  368. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  369. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  370. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  371. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  372. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  373. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  374. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  375. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  376. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  377. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  378. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  379. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  380. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  381. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  382. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  383. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  384. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  385. William M, et al. 2018. J Immunol. 200:4102. PubMed
  386. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  387. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  388. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  389. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  390. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  391. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  392. Lee SA, et al. 2021. Cells. 10:. PubMed
  393. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  394. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  395. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  396. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  397. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  398. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  399. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  400. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  401. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  402. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  403. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  404. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  405. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  406. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  407. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  408. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  409. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  410. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  411. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  412. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  413. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  414. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  415. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  416. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  417. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  418. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  419. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  420. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  421. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  422. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  423. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  424. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  425. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  426. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  427. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  428. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  429. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  430. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  431. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  432. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  433. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  434. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  435. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  436. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  437. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  438. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  439. Sibler E, et al. 2021. Cells. 10:. PubMed
  440. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  441. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  442. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  443. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  444. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  445. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  446. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  447. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  448. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  449. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  450. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  451. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  452. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  453. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  454. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  455. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  456. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  457. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312800 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
CD16/32
Specificity Alt (DOES NOT SHOW ON TDS):
CD16/32
App Abbreviation (DOES NOT SHOW ON TDS):
FC,IP,Block
UniProt
View information about CD16/32 on UniProt.org

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Go To Top Version: 2    Revision Date: 01/23/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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