FITC anti-human CD18 Antibody anti-CD18

Clone: CBR LFA-1/2 (See other available formats)
Regulatory Status: RUO
Other Names: Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2, b2 integrin, beta 2 integrin
Isotype: Mouse IgG1, κ
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CBRspaceLFA-1slash2_FITC_CD18_Antibody_FC_031915 — Human peripheral blood lymphocytes were stained with CD18 (clone CBR LFA-1/2) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).

Compare all formats See FITC spectral data

Cat #	Size	Price	Save
366305	25 tests	¥22,220
366306	100 tests	¥53,020

Description

CD18, also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin, is a 90 - 95 kD type I glycoprotein. CD18 non-covalently associates with CD11a, CD11b, or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in the adhesion and signaling in hematopoietic cells.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Purified human LFA-1
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)
Application Notes: Additional reported applications (for the relevant formats of this clone) include: activation of LFA-1 and MAC-1^1,2. The LEAF™ or Ultra-LEAF™ purified antibody (Endotoxin < EU/µg, Azide-Free, 0.2 µm filtered) is recommended for function assays (contact our custom solutions team).
RRID: AB_2565529 (BioLegend Cat. No. 366305)
AB_2565529 (BioLegend Cat. No. 366306)

Antigen Details

Structure: 90 - 95 kD type I transmembrane glycoprotein.
Distribution: Leukocytes.
Function: Cell adhesion and signaling.
Interaction: Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c
Ligand/Receptor: ICAMs.
Cell Type: Leukocytes
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer TA. 1994. Cell 76:301.
Gene ID: 3689 View all products for this Gene ID
UniProt: View information about CD18 on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

Related Products

Description	Clone	Applications

Related Pages & Pathways

Pathways

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Other Formats

View All CD18 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human CD18	CBR LFA-1/2	FC
PE anti-human CD18	CBR LFA-1/2	FC
APC anti-human CD18	CBR LFA-1/2	FC
FITC anti-human CD18	CBR LFA-1/2	FC
PE/Cyanine7 anti-human CD18	CBR LFA-1/2	FC
Alexa Fluor® 647 anti-human CD18	CBR LFA-1/2	FC
APC/Fire™ 750 anti-human CD18	CBR LFA-1/2	FC
PerCP/Cyanine5.5 anti-human CD18	CBR LFA-1/2	FC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 03/19/2015

For Research Use Only. Not for diagnostic or therapeutic use.

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