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FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
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30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Save
103107 50 µg ¥7,920
103108 500 µg ¥19,650
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  2. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  3. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  4. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  5. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  6. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  7. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  8. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  9. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  10. Sefik E, et al. 2022. Nature. 606:585. PubMed
  11. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  12. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  13. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  14. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  15. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  16. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  17. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  18. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  19. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  20. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  21. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  22. Zheng Z, et al. 2022. Cells. 11: . PubMed
  23. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  24. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  25. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  26. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  27. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  28. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  29. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  30. Liu X, et al. 2022. Pain. 163:508. PubMed
  31. González H, et al. 2022. Cell. 185:729. PubMed
  32. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  33. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  34. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  35. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  36. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  37. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  38. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  39. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  40. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  41. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  42. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  43. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  44. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  45. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  46. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  47. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  48. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  49. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  50. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  51. Li L, et al. 2023. iScience. 26:106095. PubMed
  52. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  53. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  54. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  55. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  56. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  57. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  58. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  59. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  60. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  61. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  62. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  63. Wang X, et al. 2023. Nature. 618:808. PubMed
  64. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  65. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  66. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  67. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  68. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  69. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  70. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  71. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  72. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  73. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  74. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  75. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  76. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  77. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  78. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  79. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  80. Zhu H, et al. 2018. Elife. 7:. PubMed
  81. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  82. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  83. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  84. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  85. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  86. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  87. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  88. Saito S, et al. 2020. Nutrients. 12:. PubMed
  89. Liu X, et al. 2020. Nature. . PubMed
  90. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  91. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  92. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  93. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  94. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  95. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  96. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  97. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  98. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  99. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  100. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  101. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  102. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  103. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  104. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  105. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  106. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  107. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  108. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  109. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  110. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  111. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  112. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  113. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  114. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  115. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  116. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  117. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  118. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  119. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  120. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  121. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  122. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  123. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  124. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  125. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  126. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  127. Plein A, et al. 2018. Nature. 562:223. PubMed
  128. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  129. Green DP, et al. 2019. Neuron. 101:412. PubMed
  130. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  131. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  132. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  133. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  134. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  135. Zhang X, et al. 2022. Cells. 11:. PubMed
  136. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  137. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  138. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  139. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  140. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  141. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  142. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  143. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  144. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  145. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  146. Li J, et al. 2020. Elife. 9:00. PubMed
  147. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  148. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  149. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  150. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  151. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  152. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  153. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  154. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  155. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  156. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  157. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  158. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  159. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  160. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  161. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  162. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  163. Wan X, et al. 2018. Nature. 560:107. PubMed
  164. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  165. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  166. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  167. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  168. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  169. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  170. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  171. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  172. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  173. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  174. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  175. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  176. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  177. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  178. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  179. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  180. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  181. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  182. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  183. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  184. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  185. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  186. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  187. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  188. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  189. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  190. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  191. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  192. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  193. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  194. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  195. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  196. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  197. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  198. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  199. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  200. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  201. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  202. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  203. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  204. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  205. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  206. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  207. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  208. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  209. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  210. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  211. Long JT, et al. 2022. Elife. 11:. PubMed
  212. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  213. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  214. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  215. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  216. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  217. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  218. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  219. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  220. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  221. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  222. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  223. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  224. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  225. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  226. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  227. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  228. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  229. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  230. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  231. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  232. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  233. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  234. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  235. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  236. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  237. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  238. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  239. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  240. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  241. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  242. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  243. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  244. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  245. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  246. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  247. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  248. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  249. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  250. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  251. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  252. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  253. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  254. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  255. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  256. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  257. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  258. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  259. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  260. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  261. Sheng J, et al. 2021. eLife. 10:00. PubMed
  262. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  263. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  264. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  265. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  266. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  267. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  268. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  269. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  270. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  271. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  272. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  273. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  274. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  275. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  276. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  277. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  278. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  279. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  280. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  281. Dingler FA, et al. 2020. Mol Cell. . PubMed
  282. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  283. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  284. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  285. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  286. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  287. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  288. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  289. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  290. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312972 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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