PE anti-human CD36L1 SCARB1, SR-BI Antibody anti-CD36L1

Clone: m1B9 (See other available formats)
Regulatory Status: RUO
Other Names: SR-BI, SRB1, SR-B1, SRBI, CLA-1, CLA1, HDLQTL6
Isotype: Mouse IgG1, κ
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Product Citations: publications

Human monocyte-derived dendritic cells were stained with CD36L1 (clone m1B9) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).

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Cat #	Size	Price	Save
363203	25 tests	¥33,660
363204	100 tests	¥76,340

Description

Scavenger receptor class B type I (SCARB1), also known as CD36L1, is an integral membrane protein found in numerous cell types and tissues that is mainly expressed in the liver and the adrenal glands. Its primary function is facilitating the uptake of cholesteryl esters from high-density lipoproteins (HDL) due to its high affinity to HDL. This function serves to lower the risk of development of atherosclerosis. SCARB1 is also able to bind to other lipoproteins such as LDL, OxLDL, and VLDL. SCARB1 is also likely to be involved in pathogen recognition through its recognition of mycobacteria and other viral proteins and regulates vitamin E levels in the tissue.

Product Details

Technical data sheet

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2564209 (BioLegend Cat. No. 363203)
AB_2564209 (BioLegend Cat. No. 363204)

Antigen Details

Structure: Integral membrane glycoprotein.
Distribution: Macrophages, hepatocytes, dendritic cells, adrenocortical cells, adipocytes, trophoblastic cells.
Function: Involved in the uptake of high density lipoproteins (HDL), phagocytosis of apoptotic cells, and pathogen recognition. Receptor target of the hepatitis C virus.
Ligand/Receptor: Phosphatidylserine, HDL, apoB-containing lipoproteins, LDL, vitamin E.
Cell Type: Macrophages, Dendritic cells
Biology Area: Cell Adhesion, Cell Biology, Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Acton S, et al. 1996. Science. 5248:518.
2. Rigotti A, et al. 2003. Endocr. Rev. 24:357.
3. Valacchi G, et al. 2011. Ann. N. Y. Acad. Sci. 1229:E1.
4. Scarselli E, et al. 2002. EMBO J. 21:5017.
5. Mardones P, et al. 2002. J. Nutr. 132:443.
Gene ID: 949 View all products for this Gene ID
UniProt: View information about CD36L1 on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Description	Clone	Applications

Related Pages & Pathways

Related FAQs

What type of PE do you use in your conjugates?: We use R-PE in our conjugates.

Other Formats

View All CD36L1 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human CD36L1 (SCARB1, SR-BI)	m1B9	FC
PE anti-human CD36L1 (SCARB1, SR-BI)	m1B9	FC
PerCP/Cyanine5.5 anti-human CD36L1 (SCARB1, SR-BI)	m1B9	FC
APC anti-human CD36L1 (SCARB1, SR-BI)	m1B9	FC
PE/Cyanine7 anti-human CD36L1 (SCARB1, SR-BI)	m1B9	FC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 09/16/2014

For Research Use Only. Not for diagnostic or therapeutic use.

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