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- Clone
- RR8-1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Vα11 T-cell receptor,T cell receptor alpha 11
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
C57BL/6 mouse lymph node stained with TCR Vα11 (RR8-1) PE and CD3 (145-2C11) APC
| Cat # | Size | Price | Save |
|---|---|---|---|
| 139903 | 25 µg | ¥22,970 | |
| 139904 | 100 µg | ¥41,300 |
Vα11 T cell receptor (TCR Vα11) is a variant of TCR α chain and, along with TCR β chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through the interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The RR8-1 antibody is specific for b and d haplotypes of TCR Vα11.1 and Vα11.2, but not for Vα11.3. It does not react with a and c haplotypes of TCR Vα11.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse T-cell clone B10
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Jameson SC, et al. 1991. J. Immunol. 147:3185. (FC)
- RRID
-
AB_10640825 (BioLegend Cat. No. 139903)
AB_10640825 (BioLegend Cat. No. 139904)
Antigen Details
- Structure
- Member of the immunoglobulin superfamily, Vα11 is a variant of the TCR α chain which associates with the TCR β chain to form the TCR heterodimer.
- Distribution
-
Subset of TCR αβ+ T cells.
- Function
- Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune responses.
- Ligand/Receptor
- MHC-peptide complex
- Cell Type
- T cells
- Biology Area
- Adaptive Immunity, Immunology
- Molecular Family
- TCRs
- Gene ID
- 21473 View all products for this Gene ID
- UniProt
- View information about TCR Valpha11.1 11.2 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All TCR Vα11.1, 11.2 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-mouse TCR Vα11.1, 11.2 | RR8-1 | FC |
| TotalSeq™-C0984 anti-mouse TCR Vα11.1, 11.2 | RR8-1 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
PE anti-mouse TCR Vα11.1, 11.2
C57BL/6 mouse lymph node stained with TCR Vα11 (RR8-1) PE an... -
TotalSeq™-C0984 anti-mouse TCR Vα11.1, 11.2
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