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- Clone
- HIP2 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- HCDM listed
- Other Names
- ITGA2B, Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, CD41
- Isotype
- Mouse IgG3, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Human peripheral blood platelets stained with purified CD41b (clone HIP2) (filled histogram) or mouse IgG3, followed by anti-mouse IgG FITC.
CD41b is a β chain of glycoprotein IIb (known as CD41) which is associated with glycoprotein IIIa (or integrin β3, CD61) and forms CD41/CD61 complex. CD41/CD61 mediates platelet adhesion and aggregation through the interaction with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is expressed by platelets and megakaryocytes.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Leong L, et al. 1995. J. Cell. Sci. 108:3817.
- RRID
-
AB_11218799 (BioLegend Cat. No. 354802)
Antigen Details
- Structure
- A β chain of glycoprotein IIb that associates with glycoprotein IIIa to form a CD41/CD61 complex
- Distribution
-
Platelets, Megakaryocytes
- Function
- Platelet activation and aggregation
- Cell Type
- Platelets, Megakaryocytes
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules, Protein Kinases/Phosphatase
- Antigen References
-
1. Nakahata T, et al. 1994 Leuk. Lymphoma 13:401.
- Gene ID
- 3674 View all products for this Gene ID
- UniProt
- View information about CD41b on UniProt.org
Related FAQs
Other Formats
View All CD41b Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD41b | HIP2 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD41b
Human peripheral blood platelets stained with purified CD41b...
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