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- Clone
- AST-3T (See other available formats)
- Regulatory Status
- RUO
- Other Names
- integrin b5, integrin beta 5, ITGB5
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human cervical cancer cell line HeLa stained with AST-3T PE.
Integrins are a family of transmembrane proteins. A total 17 integrin α chains and 8 β chains have been identified. The association of integrin α and β chains forms 25 integrin complexes which serve as extracellular matrix receptors and play important roles in cell adhesion and development. Integrin β5 is a 95 kD glycoprotein heterodimer with the αV subunit and is found on many types of tissue cells, such as epithelial cells, endothelial cells, keratinocytes, and osteoblastic cells. The αV/β5 integrin complex binds to vitronectin.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_2234046 (BioLegend Cat. No. 345202)
Antigen Details
- Structure
- Integrin family, Ig superfamily, associates with αV subunit
- Distribution
-
Epithelial cells, endothelial cells, keratinocytes, osteoblastic cells
- Function
- Cell adhesion
- Ligand/Receptor
- vitronectin
- Cell Type
- Endothelial cells, Epithelial cells, Osteoclasts
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules
- Antigen References
-
1. Kim JP. et al. 1994. J. Bio. Chem. 269:26926
2. Cheng SL. et al. 2000. J. Cell Biochem. 77:265
3. Aplin JD. et al. 1996. Mol. Hum. Reprod. 2:527 - Gene ID
- 3693 View all products for this Gene ID
- UniProt
- View information about Integrin beta 5 on UniProt.org
Related FAQs
Other Formats
View All integrin β5 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human integrin β5 | AST-3T | FC |
| PE anti-human integrin β5 | AST-3T | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human integrin β5
Human cervical cancer cell line HeLa stained with AST-3T PE. -
PE anti-human integrin β5
Human cervical cancer cell line HeLa stained with AST-3T PE.
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